mitogen-activated protein kinase 6

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Synonym

2610021I23Rik, Extracellular signal-regulated kinase 3, Prkm6, Mitogen-activated protein kinase 6, mitogen-activated protein kinase 6, ERK-3, Mapk6, D130053K17Rik, Mapk4, ERK3, Erk-3 related, Prkm4, Mapk63, Erk3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.95 cerebellum:7.85 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.06 spine:7.78 retina:6.02 eye:6.02 artery/aorta:- vein:6.96 lymphnode:7.21 peripheral blood:- spleen:6.42 thymus:- bone marrow:7.48 adipose:7.36 bone:6.95 skin:6.12
CAGE cerebrum:3.37 cerebellum:- brain stem:3.76 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.06 retina:- eye:- artery/aorta:3.25 vein:- lymphnode:2.90 peripheral blood:- spleen:2.71 thymus:2.82 bone marrow:- adipose:- bone:2.72 skin:3.44
RNA-seq cerebrum:4.78 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.04 placenta:8.25 prostate:6.78 ovary:6.50 testis:11.09 heart:6.96 muscle:6.88 esophagus:- stomach:7.37 intestine:7.89 colon:- liver/hepato:6.97 lung:6.35 bladder:6.73 kidney:6.66 pituitary:6.57 thyroid/parathyroid:- adrenal gland:6.39 pancreas:6.77 breast:7.02 salivary:6.33
CAGE uterus:3.22 placenta:3.89 prostate:2.79 ovary:2.99 testis:6.08 heart:- muscle:- esophagus:- stomach:2.95 intestine:4.49 colon:4.02     liver/hepato:3.07    lung:2.93 bladder:3.01 kidney:- pituitary:3.18 thyroid/parathyroid:- adrenal gland:3.07 pancreas:1.61 breast:3.31 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.83 esophagus:- stomach:- intestine:- colon:-     liver/hepato:4.52        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_015806
Gene ID 50772
Unigene ID -
Probe set ID 1419168_at  [Mouse430_2]
Ensembl ID ENSMUSG00000042688

Orthologous Gene

Human[1]  NM_002748
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR008350  ERK3/4 MAP kinase
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8444355
8889548
10349636
10657254
10922068
11042159
11076861
11217851
12466851
12477932
12504858
12520002
12808096
12904583
14610273
14681479
15489334
15538386
15577943
15729360
16141072
16141073
16973613
18287559
18799693
19470755
19805361
20927325
21267068
21505187
22508986

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0000165  MAPKKK cascade
GO:0016310  phosphorylation
GO:0006468  protein amino acid phosphorylation

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0016301  kinase activity
GO:0004707  MAP kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups