gamma-aminobutyric acid (GABA) B receptor, 1

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Synonym

GABA-B receptor 1, bM573K1.1, Gb1, GABA-B-R1, GABAbR1, Gabbr1, gamma-aminobutyric acid (GABA-B) receptor, 1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:456.70

cerebellum:110.50

brain stem:254.20

corpus callosum/glia:-

pineal gland:-

peripheral nerve:152.90

spine:94.60

retina:192.90

eye:91.20

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:65.80

thymus:59.30

bone marrow:-

adipose:-

bone:62.60

skin:47.50

GeneChip

cerebrum:11.81

cerebellum:11.56

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:10.79

spine:10.97

retina:9.48

eye:7.30

artery/aorta:-

vein:8.29

lymphnode:7.49

peripheral blood:-

spleen:7.81

thymus:-

bone marrow:7.01

adipose:6.82

bone:7.01

skin:7.99

CAGE

cerebrum:5.87

cerebellum:-

brain stem:5.94

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:5.69

retina:-

eye:-

artery/aorta:2.83

vein:-

lymphnode:3.22

peripheral blood:-

spleen:2.63

thymus:3.92

bone marrow:-

adipose:-

bone:3.06

skin:3.61

RNA-seq

cerebrum:83.97

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:11.50

testis:7.40

heart:18.60

muscle:-

esophagus:-

stomach:-

intestine:-

colon:17.60

liver/hepato:-

lung:10

bladder:66.20

kidney:24.20

pituitary:142.10

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:13.10

salivary:-

GeneChip

uterus:8.37

placenta:6.18

prostate:6.95

ovary:8.10

testis:7.14

heart:6.41

muscle:6.60

esophagus:-

stomach:6.96

intestine:6.80

colon:-

liver/hepato:6.05

lung:7.53

bladder:7.44

kidney:6.98

pituitary:7.87

thyroid/parathyroid:-

adrenal gland:8.44

pancreas:7.79

breast:7.01

salivary:6.87

CAGE

uterus:3.29

placenta:2.47

prostate:2.61

ovary:3.47

testis:1.18

heart:-

muscle:-

esophagus:-

stomach:3.25

intestine:2.16

colon:2.16

liver/hepato:1.70

lung:3.41

bladder:3.71

kidney:-

pituitary:3.58

thyroid/parathyroid:-

adrenal gland:3.21

pancreas:2.33

breast:2.59

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.98

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0.83

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_019439
Gene ID	54393
Unigene ID	Mm.32191
Probe set ID	1455021_at [Mouse430_2]
Ensembl ID	ENSMUSG00000024462

Orthologous Gene

Human[4]	NM_001470, NM_021903, NM_021904
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR000337	GPCR, family 3
IPR002455	GPCR, family 3, gamma-aminobutyric acid receptor, type B
IPR002456	GPCR, family 3, gamma-aminobutyric acid receptor, type B1
IPR000436	Sushi/SCR/CCP

Gene Ontology (GO ID)

Biological Process

GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007214	gamma-aminobutyric acid signaling pathway
GO:0007194	negative regulation of adenylate cyclase activity
GO:0008285	negative regulation of cell proliferation
GO:0033602	negative regulation of dopamine secretion
GO:0032811	negative regulation of epinephrine secretion
GO:0014053	negative regulation of gamma-aminobutyric acid secretion
GO:0050805	negative regulation of synaptic transmission
GO:0001649	osteoblast differentiation
GO:0014049	positive regulation of glutamate secretion
GO:0060124	positive regulation of growth hormone secretion
GO:0030817	regulation of cAMP biosynthetic process
GO:0014048	regulation of glutamate secretion
GO:0007165	signal transduction

Cellular Component

GO:0030673	axolemma
GO:0030054	cell junction
GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0043198	dendritic shaft
GO:0043197	dendritic spine
GO:0005789	endoplasmic reticulum membrane
GO:0005615	extracellular space
GO:0016021	integral to membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0016020	membrane
GO:0045121	membrane raft
GO:0031966	mitochondrial membrane
GO:0043005	neuron projection
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane
GO:0042734	presynaptic membrane
GO:0045202	synapse
GO:0008021	synaptic vesicle

Molecular Function

GO:0004930	G-protein coupled receptor activity
GO:0004965	GABA-B receptor activity
GO:0005515	protein binding
GO:0004871	signal transducer activity
GO:0008134	transcription factor binding

gamma-aminobutyric acid (GABA) B receptor, 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function