glycogen synthase kinase 3 alpha

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Synonym

Gsk3a, glycogen synthase kinase 3 alpha

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:10.22

cerebellum:10.09

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:10.07

spine:10.21

retina:9.74

eye:9.70

artery/aorta:-

vein:9.44

lymphnode:9.60

peripheral blood:-

spleen:9.68

thymus:-

bone marrow:9.89

adipose:9.64

bone:9.63

skin:9.32

CAGE

cerebrum:4.60

cerebellum:-

brain stem:4.71

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.73

retina:-

eye:-

artery/aorta:4.32

vein:-

lymphnode:3.80

peripheral blood:-

spleen:3.97

thymus:4.16

bone marrow:-

adipose:-

bone:4.02

skin:3.88

RNA-seq

cerebrum:64.09

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:9.60

placenta:9.07

prostate:9.29

ovary:9.48

testis:9.60

heart:9.77

muscle:10.16

esophagus:-

stomach:9.44

intestine:9.69

colon:-

liver/hepato:8.92

lung:9.50

bladder:9.69

kidney:9.53

pituitary:9.51

thyroid/parathyroid:-

adrenal gland:9.70

pancreas:9.21

breast:9.51

salivary:9.94

CAGE

uterus:3.85

placenta:3.54

prostate:3.55

ovary:3.91

testis:4.60

heart:-

muscle:-

esophagus:-

stomach:4.01

intestine:4.61

colon:4.18

liver/hepato:3.79

lung:3.80

bladder:3.94

kidney:-

pituitary:3.89

thyroid/parathyroid:-

adrenal gland:4.05

pancreas:3.41

breast:3.62

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:17.02

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:6.68

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001031667
Gene ID	606496
Unigene ID	-
Probe set ID	1435638_at [Mouse430_2]
Ensembl ID	ENSMUSG00000057177

Orthologous Gene

Human[2]	NM_019884
Rat[1]	NM_017344

Chromosomal Region

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0003214	cardiac left ventricle morphogenesis
GO:0016477	cell migration
GO:0032869	cellular response to insulin stimulus
GO:0071285	cellular response to lithium ion
GO:0071407	cellular response to organic cyclic substance
GO:0006349	genetic imprinting
GO:0005977	glycogen metabolic process
GO:0044027	hypermethylation of CpG island
GO:0008286	insulin receptor signaling pathway
GO:0046325	negative regulation of glucose import
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0009968	negative regulation of signal transduction
GO:0032007	negative regulation of TOR signaling pathway
GO:0051348	negative regulation of transferase activity
GO:0007399	nervous system development
GO:0016310	phosphorylation
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0045823	positive regulation of heart contraction
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0010800	positive regulation of peptidyl-threonine phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006468	protein amino acid phosphorylation
GO:0003073	regulation of systemic arterial blood pressure
GO:0016055	Wnt receptor signaling pathway

Molecular Function

GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0034236	protein kinase A catalytic subunit binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0050321	tau-protein kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

glycogen synthase kinase 3 alpha

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Molecular Function