tumor protein p73

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:38 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001108696
Gene ID 362675
Unigene ID Rn.103860
Probe set ID -
Ensembl ID ENSRNOG00000024707

Orthologous Gene

Human[4]  NM_001126240, NM_001126241, NM_001126242, NM_001204184, NM_001204185, NM_001204186, NM_001204187, NM_001204188, NM_001204189, NM_001204190, NM_001204191, NM_001204192, NM_005427
Mouse[5]  NM_001126330, NM_001126331, NM_011642, NM_001204184, NM_001204185, NM_001204186, NM_001204187, NM_001204188, NM_001204189, NM_001204190, NM_001204191, NM_001204192, NM_005427

Chromosomal Region

5q36  [170,848,979  -  171,078,739]

Gene Family (Interpro ID)

IPR015551  Cellular tumour antigen p53
IPR002117  p53 tumour antigen
IPR011615  p53, DNA-binding
IPR008967  p53-like transcription factor, DNA-binding
IPR012346  p53/RUNT-type transcription factor, DNA-binding domain
IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR021129  Sterile alpha motif, type 1
IPR011510  Sterile alpha motif, type 2
IPR013761  Sterile alpha motif-type

Link to Pubmed  (Pubmed ID)

9288759
9796703
10383132
10634515
10760569
11051237
11103943
11139314
11720444
11870517
12167641
12928725
14587038
14960496
15492805
15492852
15716325
15723718
15805112
16254107
16645632
16818688
16928264
17011986
17353261
17446929
18362891
19194497
20519366
20883783
22713868
23086675
23263379
23354845

Gene Ontology  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0007050  cell cycle arrest
GO:0034644  cellular response to UV
GO:0033326  cerebrospinal fluid secretion
GO:0048546  digestive tract morphogenesis
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0006978  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0030900  forebrain development
GO:0031571  G1/S DNA damage checkpoint
GO:0021766  hippocampus development
GO:0006954  inflammatory response
GO:0001822  kidney development
GO:0043508  negative regulation of JUN kinase activity
GO:0043524  negative regulation of neuron apoptosis
GO:0045665  negative regulation of neuron differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048666  neuron development
GO:0043065  positive regulation of apoptosis
GO:0045793  positive regulation of cell size
GO:0048714  positive regulation of oligodendrocyte differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0009791  post-embryonic development
GO:0051262  protein tetramerization
GO:0043523  regulation of neuron apoptosis
GO:0001836  release of cytochrome c from mitochondria
GO:0006974  response to DNA damage stimulus
GO:0010332  response to gamma radiation
GO:0010243  response to organic nitrogen
GO:0010165  response to X-ray
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0000785  chromatin
GO:0005829  cytosol
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003684  damaged DNA binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0042802  identical protein binding
GO:0002039  p53 binding
GO:0019901  protein kinase binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding