runt related transcription factor 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001060475
Gene ID 367218
Unigene ID Rn.83672
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

9q12  [11,792,104  -  12,025,219]

Gene Family (Interpro ID)

IPR013524  Acute myeloid leukemia 1 (AML 1)/Runt
IPR000040  Acute myeloid leukemia 1 protein (AML 1)/Runt
IPR008967  p53-like transcription factor, DNA-binding
IPR012346  p53/RUNT-type transcription factor, DNA-binding domain
IPR016554  Transcription factor, Runt-related, RUNX

Link to Pubmed  (Pubmed ID)

9182765
9632804
9651525
11784711
12112009
12369786
12403780
12697832
12815054
12951324
14982932
15013103
15051730
15107836
15456860
15537653
15668335
16115867
16322555
16443755
16543677
16610234
17265428
17334410
17708712
17950631
18061509
18171674
18432284
18701816
19075196
19121369
19124839
19170063
19423655
19739101
19822991
19893245
20019778
20093419
20097749
20197312
20568992
20818503
21221986
21302441
21412826
21893222
22008669
22009963
22407386
22547067
22713854
22827283
22873791
22906827
23517179

Gene Ontology  (GO ID)

Biological Process

GO:0030509  BMP signaling pathway
GO:0048469  cell maturation
GO:0002063  chondrocyte development
GO:0002062  chondrocyte differentiation
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0001958  endochondral ossification
GO:0045879  negative regulation of smoothened signaling pathway
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0042475  odontogenesis of dentine-containing tooth
GO:0002076  osteoblast development
GO:0001649  osteoblast differentiation
GO:0002051  osteoblast fate commitment
GO:0008284  positive regulation of cell proliferation
GO:0032332  positive regulation of chondrocyte differentiation
GO:0045778  positive regulation of ossification
GO:0045669  positive regulation of osteoblast differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0040036  regulation of fibroblast growth factor receptor signaling pathway
GO:0042487  regulation of odontogenesis of dentine-containing tooth
GO:0030278  regulation of ossification
GO:0045667  regulation of osteoblast differentiation
GO:0001501  skeletal system development
GO:0048705  skeletal system morphogenesis
GO:0048863  stem cell differentiation
GO:0030217  T cell differentiation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0000790  nuclear chromatin
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0005524  ATP binding
GO:0043425  bHLH transcription factor binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0019904  protein domain specific binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding