optineurin

Synonym

Huntingtin-interacting protein HYPL, NEMO-related protein, TFIIIA-IntP, OPTN, FIP2, HYPL, open angle, Transcription factor IIIA-interacting protein, TFIIIA-INTP, E3-14.7K-interacting protein, FIP-2, HIP7, optineurin, Optineurin, Optic neuropathy-inducing protein, GLC1E

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:78.20

cerebellum:25.20

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:153.40

spine:224.60

retina:-

eye:111.70

artery/aorta:179.90

vein:199.90

lymphnode:10.10

peripheral blood:18.20

spleen:75.60

thymus:12.90

bone marrow:59

adipose:80.70

bone:115.20

skin:81.60

GeneChip

cerebrum:7.90

cerebellum:7.82

brain stem:8.28

corpus callosum/glia:7.71

pineal gland:-

peripheral nerve:8.43

spine:8.04

retina:-

eye:-

artery/aorta:8.09

vein:8.21

lymphnode:7.76

peripheral blood:-

spleen:7.89

thymus:7.03

bone marrow:7.50

adipose:8.20

bone:-

skin:7.86

CAGE

cerebrum:4.37

cerebellum:-

brain stem:4.50

corpus callosum/glia:4.01

pineal gland:3.97

peripheral nerve:-

spine:4.32

retina:-

eye:-

artery/aorta:4.13

vein:4.11

lymphnode:3.53

peripheral blood:-

spleen:4.06

thymus:3.24

bone marrow:-

adipose:4.46

bone:-

skin:-

RNA-seq

cerebrum:5.36

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.90

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:5.31

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:72.90

placenta:69.20

prostate:56.30

ovary:111.80

testis:121.10

heart:102.20

muscle:502.30

esophagus:-

stomach:-

intestine:64.80

colon:50.90

liver/hepato:73.90

lung:83.10

bladder:-

kidney:62.40

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:8.90

breast:111.50

salivary:-

GeneChip

uterus:7.39

placenta:7.29

prostate:7.03

ovary:7.98

testis:8.60

heart:8.14

muscle:10.11

esophagus:8.32

stomach:7.47

intestine:7.77

colon:7.11

liver/hepato:7.69

lung:7.93

bladder:-

kidney:7.70

pituitary:7.52

thyroid/parathyroid:7.13

adrenal gland:8.27

pancreas:7.18

breast:7.47

salivary:7.74

CAGE

uterus:4.03

placenta:3.77

prostate:4.12

ovary:4.38

testis:4.56

heart:4.83

muscle:6.43

esophagus:4.26

stomach:-

intestine:4.44

colon:3.83

liver/hepato:4.19

lung:4.07

bladder:4.15

kidney:4.08

pituitary:4.04

thyroid/parathyroid:3.53

adrenal gland:-

pancreas:3.20

breast:4.69

salivary:3.75

RNA-seq

uterus:-

placenta:-

prostate:5.07

ovary:5.58

testis:5.34

heart:5.23

muscle:8.05

esophagus:-

stomach:-

intestine:-

colon:5.55

liver/hepato:2.95

lung:4.80

bladder:-

kidney:4.34

pituitary:-

thyroid/parathyroid:5.49

adrenal gland:4.44

pancreas:-

breast:5.70

salivary:-

IDs

Refseq ID	NM_021980
Gene ID	10133
Unigene ID	Hs.332706
Probe set ID	202074_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000123240
GTEx ID	ENSG00000123240

Orthologous Gene

Mouse[1]	NM_181848
Rat [0]

Chromosomal Region

10p13 [13,141,449 - 13,180,291]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0008219	cell death
GO:0000086	G2/M transition of mitotic cell cycle
GO:0007030	Golgi organization
GO:0090161	Golgi ribbon formation
GO:0043001	Golgi to plasma membrane protein transport
GO:0000278	mitotic cell cycle
GO:0000042	protein targeting to Golgi
GO:0007165	signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005794	Golgi apparatus
GO:0000139	Golgi membrane
GO:0005654	nucleoplasm
GO:0048471	perinuclear region of cytoplasm
GO:0005802	trans-Golgi network

Molecular Function

GO:0005515	protein binding
GO:0008022	protein C-terminus binding

optineurin

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function