adenosine deaminase, RNA-specific

Synonym

136 kDa double-stranded RNA-binding protein, Double-stranded RNA-specific adenosine deaminase, DRADA, K88dsRBP, ADAR1, ADAR, K88DSRBP, P136, IFI4, Interferon-inducible protein 4, DSRAD, G1P1, interferon-induced protein 4, IFI-4, p136, adenosine deaminase, RNA-specific, DSH, IFI-4 protein

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:173

cerebellum:50.40

brain stem:-

corpus callosum/glia:58.30

pineal gland:148.30

peripheral nerve:184

spine:224.60

retina:-

eye:217.40

artery/aorta:60

vein:466.50

lymphnode:151.70

peripheral blood:91.10

spleen:170.20

thymus:90.20

bone marrow:196.80

adipose:161.30

bone:179.10

skin:172.80

GeneChip

cerebrum:9.29

cerebellum:9.05

brain stem:9.25

corpus callosum/glia:9.02

pineal gland:-

peripheral nerve:9.42

spine:9

retina:-

eye:-

artery/aorta:9.05

vein:8.62

lymphnode:9.60

peripheral blood:-

spleen:10.02

thymus:9.74

bone marrow:8.97

adipose:8.95

bone:-

skin:8.95

CAGE

cerebrum:4.46

cerebellum:-

brain stem:4.41

corpus callosum/glia:4.55

pineal gland:4.65

peripheral nerve:-

spine:4.21

retina:-

eye:-

artery/aorta:4.27

vein:4.46

lymphnode:4.63

peripheral blood:-

spleen:4.73

thymus:4.84

bone marrow:-

adipose:4.57

bone:-

skin:-

RNA-seq

cerebrum:4.95

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.33

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.70

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:127.60

placenta:83.80

prostate:112.60

ovary:37.30

testis:86.50

heart:89.40

muscle:-

esophagus:-

stomach:85

intestine:129.60

colon:212

liver/hepato:73.90

lung:132

bladder:125.60

kidney:62.40

pituitary:232

thyroid/parathyroid:-

adrenal gland:-

pancreas:26.70

breast:204.40

salivary:-

GeneChip

uterus:9.44

placenta:8.78

prostate:9.58

ovary:9.52

testis:9.07

heart:8.49

muscle:7.27

esophagus:8.72

stomach:9.20

intestine:8.65

colon:8.91

liver/hepato:9.35

lung:9.35

bladder:-

kidney:9.19

pituitary:9.56

thyroid/parathyroid:9.43

adrenal gland:9.24

pancreas:8.10

breast:9.46

salivary:8.61

CAGE

uterus:4.40

placenta:4.43

prostate:4.36

ovary:4.63

testis:4.26

heart:4.11

muscle:3.11

esophagus:4.32

stomach:-

intestine:4.66

colon:4.24

liver/hepato:4.39

lung:4.52

bladder:4.19

kidney:4.22

pituitary:4.39

thyroid/parathyroid:4.41

adrenal gland:-

pancreas:3.99

breast:4.40

salivary:4.05

RNA-seq

uterus:-

placenta:-

prostate:4.86

ovary:5.71

testis:5.01

heart:3.48

muscle:2.56

esophagus:-

stomach:-

intestine:-

colon:4.34

liver/hepato:4.36

lung:4.84

bladder:-

kidney:4.62

pituitary:-

thyroid/parathyroid:4.71

adrenal gland:5.13

pancreas:-

breast:4.33

salivary:-

IDs

Refseq ID	NM_001025107
Gene ID	103
Unigene ID	Hs.12341
Probe set ID	201786_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000160710
GTEx ID	ENSG00000160710

Orthologous Gene

Mouse[3]	NM_001038587, NM_001146296, NM_019655
Rat [0]

Chromosomal Region

1q21.3 [154,554,538 - 154,600,475]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001159	Double-stranded RNA binding
IPR014720	Double-stranded RNA-binding-like
IPR000607	Double-stranded RNA-specific adenosine deaminase (DRADA)
IPR011991	Winged helix repressor DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0006382	adenosine to inosine editing
GO:0016553	base conversion or substitution editing
GO:0019221	cytokine-mediated signaling pathway
GO:0051607	defense response to virus
GO:0010467	gene expression
GO:0031047	gene silencing by RNA
GO:0045087	innate immune response
GO:0016556	mRNA modification
GO:0006397	mRNA processing
GO:0043066	negative regulation of apoptosis
GO:0045070	positive regulation of viral genome replication
GO:0006611	protein export from nucleus
GO:0006606	protein import into nucleus
GO:0009615	response to virus
GO:0060337	type I interferon-mediated signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0003677	DNA binding
GO:0003726	double-stranded RNA adenosine deaminase activity
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0003723	RNA binding

adenosine deaminase, RNA-specific

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function