kelch repeat and BTB (POZ) domain containing 10

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Synonym

Kelch repeat and BTB domain-containing protein 10, Kel-like protein 23, KBTBD10, Kelch-related protein 1, KRP1, kelch repeat and BTB (POZ) domain containing 10, SARCOSIN, Sarcosin

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:122.70 spine:- retina:- eye:23.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:12.90 bone marrow:- adipose:3267.10 bone:- skin:417.60
GeneChip cerebrum:2.95 cerebellum:2.67 brain stem:2.66 corpus callosum/glia:2.58 pineal gland:- peripheral nerve:3.78 spine:2.62 retina:- eye:- artery/aorta:2.79 vein:3.56 lymphnode:2.65 peripheral blood:- spleen:2.57 thymus:2.77 bone marrow:2.51 adipose:2.59 bone:- skin:4.60
CAGE cerebrum:0.16 cerebellum:- brain stem:0.17 corpus callosum/glia:0.43 pineal gland:1.34 peripheral nerve:- spine:0.32 retina:- eye:- artery/aorta:1.38 vein:4.03 lymphnode:2.20 peripheral blood:- spleen:0 thymus:0.57 bone marrow:- adipose:5.29 bone:- skin:-
RNA-seq cerebrum:0.76 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.35 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.21 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:326.70 ovary:- testis:4.30 heart:421.50 muscle:3957.80 esophagus:- stomach:- intestine:- colon:-     liver/hepato:137.20        lung:88    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:124.50 breast:18.60 salivary:-
GeneChip uterus:2.73 placenta:2.46 prostate:3.35 ovary:2.82 testis:3.38 heart:6.05 muscle:12.02 esophagus:8.32 stomach:2.81 intestine:4.23 colon:2.57 liver/hepato:2.53 lung:2.60 bladder:- kidney:2.58 pituitary:4.52 thyroid/parathyroid:3.24 adrenal gland:2.75 pancreas:2.64 breast:2.68 salivary:2.79
CAGE uterus:0.16 placenta:0 prostate:3.06 ovary:0.07 testis:1.55 heart:4.59 muscle:8.39 esophagus:5.04 stomach:- intestine:0.07 colon:0     liver/hepato:0    lung:1.06 bladder:3.64 kidney:0 pituitary:2.91 thyroid/parathyroid:3.49 adrenal gland:- pancreas:0 breast:0 salivary:2.95
RNA-seq uterus:- placenta:- prostate:3.67 ovary:0.99 testis:5.75 heart:6.41 muscle:11.11 esophagus:- stomach:- intestine:- colon:0.76     liver/hepato:0.10        lung:3.20    bladder:- kidney:0.49 pituitary:- thyroid/parathyroid:8.67 adrenal gland:0.29 pancreas:- breast:6.26 salivary:-

Gene Information

IDs

Refseq ID NM_006063
Gene ID 10324
Unigene ID Hs.50550
Probe set ID 219106_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000239474
GTEx ID ENSG00000239474

Orthologous Gene

Mouse[1]  NM_001081087
Rat [0]  

Chromosomal Region

2q31.1  [170,366,212  -  170,382,772]

Gene Family (Interpro ID)

IPR011333  BTB/POZ fold
IPR000210  BTB/POZ-like

Link to Pubmed  (Pubmed ID)

8889549
9655184
10713668
11583900
12477932
12692149
15489334
15983046
16396496
18029348
19424503
21890473
23676014
24268659

Gene Ontology  (GO ID)

Biological Process

GO:0030239  myofibril assembly
GO:0016567  protein ubiquitination
GO:0031275  regulation of lateral pseudopodium assembly
GO:0045661  regulation of myoblast differentiation
GO:0006941  striated muscle contraction

Cellular Component

GO:0005813  centrosome
GO:0031463  Cul3-RING ubiquitin ligase complex
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0031430  M band
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0031143  pseudopodium
GO:0001726  ruffle

Molecular Function

GO:0005515  protein binding