Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

 jump to detail

Synonym

P35SRJ, P35srj, Cbp/p300-interacting transactivator 2, MSG-related protein 1, MRG-1, CITED2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:21.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:- retina:- eye:129.30 artery/aorta:- vein:66.60 lymphnode:70.80 peripheral blood:54.70 spleen:- thymus:25.80 bone marrow:118.10 adipose:40.30 bone:102.40 skin:148.80
GeneChip cerebrum:5.88 cerebellum:7.03 brain stem:5.66 corpus callosum/glia:4.57 pineal gland:- peripheral nerve:7.25 spine:5.42 retina:- eye:- artery/aorta:7 vein:7.28 lymphnode:7.19 peripheral blood:- spleen:8.25 thymus:6.08 bone marrow:8.30 adipose:8.49 bone:- skin:8.17
CAGE cerebrum:4.14 cerebellum:- brain stem:3.98 corpus callosum/glia:3.88 pineal gland:4.63 peripheral nerve:- spine:3.45 retina:- eye:- artery/aorta:4.90 vein:4.89 lymphnode:4.72 peripheral blood:- spleen:5.65 thymus:4.26 bone marrow:- adipose:5.75 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:83.80 prostate:22.50 ovary:111.80 testis:34.60 heart:102.20 muscle:- esophagus:- stomach:21.20 intestine:64.80 colon:8.50     liver/hepato:21.10        lung:83.10    bladder:- kidney:31.20 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:74.30 salivary:-
GeneChip uterus:7.86 placenta:8.26 prostate:8.15 ovary:8.92 testis:6.89 heart:7.60 muscle:7.60 esophagus:7.69 stomach:7.43 intestine:7.49 colon:7.25 liver/hepato:7.38 lung:8.64 bladder:- kidney:8.36 pituitary:4.98 thyroid/parathyroid:9.85 adrenal gland:7.94 pancreas:7.62 breast:8.61 salivary:8.40
CAGE uterus:5.55 placenta:6.20 prostate:5.20 ovary:6.12 testis:5.10 heart:5.40 muscle:5.60 esophagus:5.19 stomach:- intestine:4.90 colon:4.71     liver/hepato:5.69    lung:5.90 bladder:4.88 kidney:5.15 pituitary:3.41 thyroid/parathyroid:6.49 adrenal gland:- pancreas:5.46 breast:5.39 salivary:5.58
RNA-seq uterus:- placenta:- prostate:0.42 ovary:0.00 testis:0.80 heart:0.75 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.80        lung:1.03    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.38 adrenal gland:0.20 pancreas:- breast:0.35 salivary:-

Gene Information

IDs

Refseq ID NM_001168388
Gene ID 10370
Unigene ID Hs.82071
Probe set ID 209357_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164442
GTEx ID ENSG00000164442

Orthologous Gene

Mouse[2]  NM_010828
Rat [0]  

Chromosomal Region

6q24.1  [139,693,393  -  139,695,757]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
8901575
9434189
9811838
9887100
10552932
10593900
11581164
11597177
11694877
11744733
12477932
12586840
12762840
12778114
12960175
14633989
15051727
15154850
15489334
16287139
16341674
16619037
16675452
17906695
17932483
18054336
18984668
19319572
19322201
19642106
19862010
19904269
20139978
20392269
20654020
20686565
20932315
21098220
21165656
21660965
22709740
22735262
22814619
23082118
23212831
23222517
23251661
23263863
23720494
23811274
24097068

Gene Ontology  (GO ID)

Biological Process

GO:0060349  bone morphogenesis
GO:0007569  cell aging
GO:0008283  cell proliferation
GO:0007417  central nervous system development
GO:0021602  cranial nerve morphogenesis
GO:0046697  decidualization
GO:0007368  determination of left/right symmetry
GO:0048596  embryonic camera-type eye morphogenesis
GO:0060971  embryonic heart tube left/right pattern formation
GO:0001892  embryonic placenta development
GO:0060136  embryonic process involved in female pregnancy
GO:0003197  endocardial cushion development
GO:0048821  erythrocyte development
GO:0030851  granulocyte differentiation
GO:0007507  heart development
GO:0001947  heart looping
GO:0002244  hemopoietic progenitor cell differentiation
GO:0070986  left/right axis specification
GO:0002089  lens morphogenesis in camera-type eye
GO:0001889  liver development
GO:0008584  male gonad development
GO:0043066  negative regulation of apoptosis
GO:0030336  negative regulation of cell migration
GO:0010629  negative regulation of gene expression
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001843  neural tube closure
GO:0003151  outflow tract morphogenesis
GO:0007422  peripheral nervous system development
GO:0045787  positive regulation of cell cycle
GO:0022409  positive regulation of cell-cell adhesion
GO:0010628  positive regulation of gene expression
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0003156  regulation of organ formation
GO:0043627  response to estrogen stimulus
GO:0034405  response to fluid shear stress
GO:0001666  response to hypoxia
GO:0009612  response to mechanical stimulus
GO:0007530  sex determination
GO:0048536  spleen development
GO:0048538  thymus development
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0001829  trophectodermal cell differentiation
GO:0001570  vasculogenesis
GO:0060412  ventricular septum morphogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0000790  nuclear chromatin
GO:0005634  nucleus

Molecular Function

GO:0003682  chromatin binding
GO:0035035  histone acetyltransferase binding
GO:0050693  LBD domain binding
GO:0005515  protein binding
GO:0046332  SMAD binding
GO:0003713  transcription coactivator activity
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity