1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)

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Synonym

1-AGPAT1, 1-acylglycerol-3-phosphate O-acyltransferase 1, 1-AGP acyltransferase 1, 1-AGPAT 1, Lysophosphatidic acid acyltransferase-alpha, AGPAT1, G15, MGC5423, Protein G15, MGC4007, LPAAT-alpha, LPAATA

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:98.40 cerebellum:75.60 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:92 spine:112.30 retina:- eye:117.50 artery/aorta:- vein:- lymphnode:111.20 peripheral blood:109.30 spleen:132.30 thymus:141.70 bone marrow:- adipose:- bone:51.20 skin:139.20
GeneChip cerebrum:7.84 cerebellum:7.53 brain stem:7.79 corpus callosum/glia:7.74 pineal gland:- peripheral nerve:8 spine:7.69 retina:- eye:- artery/aorta:7.52 vein:7.24 lymphnode:7.22 peripheral blood:- spleen:7.13 thymus:6.88 bone marrow:7.14 adipose:7.60 bone:- skin:6.96
CAGE cerebrum:3.50 cerebellum:- brain stem:3.53 corpus callosum/glia:3.56 pineal gland:3.48 peripheral nerve:- spine:3.22 retina:- eye:- artery/aorta:3.12 vein:3.14 lymphnode:2.78 peripheral blood:- spleen:2.89 thymus:2.98 bone marrow:- adipose:3.07 bone:- skin:-
RNA-seq cerebrum:4.22 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.28 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.77 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:118.50 placenta:98.40 prostate:45.10 ovary:186.30 testis:43.30 heart:102.20 muscle:40.20 esophagus:685.60 stomach:21.20 intestine:64.80 colon:110.20     liver/hepato:42.20        lung:14.70    bladder:125.60 kidney:62.40 pituitary:- thyroid/parathyroid:163.70 adrenal gland:152.40 pancreas:8.90 breast:55.80 salivary:-
GeneChip uterus:7.42 placenta:7.40 prostate:7.26 ovary:7.38 testis:8.25 heart:7.47 muscle:7.47 esophagus:6.91 stomach:7.60 intestine:7.29 colon:7.38 liver/hepato:7.65 lung:7.36 bladder:- kidney:7.92 pituitary:7.60 thyroid/parathyroid:7.74 adrenal gland:7.60 pancreas:7.16 breast:7.49 salivary:7.10
CAGE uterus:3.23 placenta:3.12 prostate:3.35 ovary:3.53 testis:3.80 heart:3.15 muscle:3.21 esophagus:3.24 stomach:- intestine:4.38 colon:3.05     liver/hepato:3.40    lung:3.19 bladder:3.34 kidney:3.39 pituitary:2.77 thyroid/parathyroid:3.35 adrenal gland:- pancreas:3.10 breast:2.87 salivary:2.99
RNA-seq uterus:- placenta:- prostate:4.77 ovary:4.50 testis:4.44 heart:3.19 muscle:3.93 esophagus:- stomach:- intestine:- colon:3.86     liver/hepato:3.77        lung:4.41    bladder:- kidney:4.45 pituitary:- thyroid/parathyroid:3.98 adrenal gland:3.28 pancreas:- breast:3.64 salivary:-

Gene Information

IDs

Refseq ID NM_032741
Gene ID 10554
Unigene ID Hs.409230
Probe set ID 215535_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000204310
GTEx ID ENSG00000204310

Orthologous Gene

Mouse[4]  NM_001163379, NM_018862
Rat[1]  NM_212458, NM_018862

Chromosomal Region

HSCHR6_MHC_APD  [32,147,333  -  32,157,217]
HSCHR6_MHC_COX  [32,084,466  -  32,094,350]
HSCHR6_MHC_QBL  [32,093,612  -  32,103,496]
HSCHR6_MHC_MCF  [32,212,421  -  32,222,305]
6p21.32  [32,135,989  -  32,145,873]
HSCHR6_MHC_MANN  [32,175,416  -  32,185,300]
HSCHR6_MHC_SSTO  [32,142,859  -  32,152,743]

Gene Family (Interpro ID)

IPR004552  1-acyl-sn-glycerol-3-phosphate acyltransferase
IPR002123  Phospholipid/glycerol acyltransferase

Link to Pubmed  (Pubmed ID)

8619474
8944226
9110174
9212163
9291118
9450025
9461603
11487472
12477932
14574404
14656967
14702039
15231747
15489334
16341674
16344560
16571775
16870193
17707131
19143821
19322201
19851445
19946888
22359512
22797925
23088713
23362303
23535732
23824909
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0016024  CDP-diacylglycerol biosynthetic process
GO:0044255  cellular lipid metabolic process
GO:0006112  energy reserve metabolic process
GO:0046474  glycerophospholipid biosynthetic process
GO:0006654  phosphatidic acid biosynthetic process
GO:0006644  phospholipid metabolic process
GO:0031325  positive regulation of cellular metabolic process
GO:0001819  positive regulation of cytokine production
GO:0001961  positive regulation of cytokine-mediated signaling pathway
GO:0019432  triglyceride biosynthetic process

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane

Molecular Function

GO:0003841  1-acylglycerol-3-phosphate O-acyltransferase activity