ubiquitin specific peptidase 16

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Synonym

ubiquitin specific protease 16, Ubiquitin carboxyl-terminal hydrolase 16, Ubp-M, Deubiquitinating enzyme 16, Ubiquitin thioesterase 16, UBP-M, ubiquitin specific peptidase 16, USP16, Ubiquitin-processing protease UBP-M, Ubiquitin-specific-processing protease 16

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:69.90 cerebellum:25.20 brain stem:- corpus callosum/glia:175 pineal gland:148.30 peripheral nerve:61.30 spine:- retina:118.60 eye:52.90 artery/aorta:659.50 vein:- lymphnode:70.80 peripheral blood:91.10 spleen:75.60 thymus:154.60 bone marrow:39.40 adipose:80.70 bone:25.60 skin:43.20
GeneChip cerebrum:6.90 cerebellum:6.77 brain stem:7.06 corpus callosum/glia:7.45 pineal gland:- peripheral nerve:7.36 spine:7 retina:- eye:- artery/aorta:6.81 vein:7.03 lymphnode:7.40 peripheral blood:- spleen:7.11 thymus:7.78 bone marrow:6.42 adipose:7.21 bone:- skin:6.71
CAGE cerebrum:3.44 cerebellum:- brain stem:3.66 corpus callosum/glia:3.08 pineal gland:3.58 peripheral nerve:- spine:3.92 retina:- eye:- artery/aorta:3.04 vein:3.15 lymphnode:3.10 peripheral blood:- spleen:3.78 thymus:3.86 bone marrow:- adipose:3.74 bone:- skin:-
RNA-seq cerebrum:3.51 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.64 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.68 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:32.80 prostate:78.90 ovary:- testis:155.80 heart:63.90 muscle:20.10 esophagus:- stomach:- intestine:32.40 colon:25.40     liver/hepato:105.60        lung:73.30    bladder:125.60 kidney:52 pituitary:- thyroid/parathyroid:163.70 adrenal gland:50.80 pancreas:8.90 breast:37.20 salivary:-
GeneChip uterus:7.15 placenta:7.72 prostate:7.47 ovary:7.32 testis:7.71 heart:6.76 muscle:7.31 esophagus:6.91 stomach:6.97 intestine:6.83 colon:5.97 liver/hepato:6.85 lung:6.98 bladder:- kidney:6.08 pituitary:7.31 thyroid/parathyroid:7.02 adrenal gland:7 pancreas:6.74 breast:7.03 salivary:6.87
CAGE uterus:3.35 placenta:4.16 prostate:3.77 ovary:3.74 testis:3.24 heart:3.53 muscle:3.73 esophagus:3.76 stomach:- intestine:3.93 colon:3.19     liver/hepato:3.78    lung:3.51 bladder:3.89 kidney:3.77 pituitary:4.14 thyroid/parathyroid:3.52 adrenal gland:- pancreas:3.06 breast:3.40 salivary:2.88
RNA-seq uterus:- placenta:- prostate:3.66 ovary:1.58 testis:1.85 heart:2.40 muscle:3.18 esophagus:- stomach:- intestine:- colon:3.26     liver/hepato:2.12        lung:3.34    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:4.53 adrenal gland:3.72 pancreas:- breast:3.48 salivary:-

Gene Information

IDs

Refseq ID NM_001001992
Gene ID 10600
Unigene ID Hs.99819
Probe set ID 218386_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000156256
GTEx ID ENSG00000156256

Orthologous Gene

Mouse[1]  NM_024258
Rat[1]  NM_001100501

Chromosomal Region

21q21.3  [30,396,950  -  30,426,809]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
9827704
10077596
10830953
12107411
12477932
12838346
14702039
15171253
15231747
15302935
15489334
15840729
17512543
17914355
18925961
19615732
21090589
21139048
21890473
21906983
21963094
22118674
22195557
22939629
23000965
23287719
24013421
24025767
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0051301  cell division
GO:0016578  histone deubiquitination
GO:0070537  histone H2A K63-linked deubiquitination
GO:0007067  mitosis
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0045901  positive regulation of translational elongation
GO:0051289  protein homotetramerization
GO:0006974  response to DNA damage stimulus
GO:0006351  transcription, DNA-dependent
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0042393  histone binding
GO:0003713  transcription coactivator activity
GO:0043130  ubiquitin binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004843  ubiquitin-specific protease activity
GO:0008270  zinc ion binding