CCCTC-binding factor (zinc finger protein)

Synonym

CTCF, Transcriptional repressor CTCF, CCCTC-binding factor (zinc finger protein), 11-zinc finger protein, CCCTC-binding factor, CTCFL paralog

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:61.60

cerebellum:50.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:112.30

retina:-

eye:11.80

artery/aorta:89.90

vein:-

lymphnode:101.10

peripheral blood:18.20

spleen:18.90

thymus:128.80

bone marrow:118.10

adipose:-

bone:-

skin:43.20

GeneChip

cerebrum:7.08

cerebellum:7.50

brain stem:6.96

corpus callosum/glia:7.24

pineal gland:-

peripheral nerve:6.99

spine:6.96

retina:-

eye:-

artery/aorta:7.17

vein:6.85

lymphnode:7.65

peripheral blood:-

spleen:7.57

thymus:8.85

bone marrow:7.68

adipose:7.10

bone:-

skin:7.29

CAGE

cerebrum:3.98

cerebellum:-

brain stem:3.79

corpus callosum/glia:3.97

pineal gland:4.08

peripheral nerve:-

spine:4.03

retina:-

eye:-

artery/aorta:3.73

vein:4.20

lymphnode:4.02

peripheral blood:-

spleen:4.11

thymus:4.94

bone marrow:-

adipose:3.77

bone:-

skin:-

RNA-seq

cerebrum:3.44

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.88

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.61

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:145.80

placenta:10.90

prostate:56.30

ovary:37.30

testis:64.90

heart:38.30

muscle:20.10

esophagus:-

stomach:21.20

intestine:32.40

colon:76.30

liver/hepato:21.10

lung:39.10

bladder:-

kidney:41.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:62.20

breast:65.10

salivary:-

GeneChip

uterus:7.64

placenta:7.39

prostate:7.60

ovary:7.57

testis:6.89

heart:6.81

muscle:7.25

esophagus:7.28

stomach:7.16

intestine:7.14

colon:7.08

liver/hepato:6.81

lung:7.15

bladder:-

kidney:7.06

pituitary:6.97

thyroid/parathyroid:7.31

adrenal gland:7.04

pancreas:6.19

breast:7.38

salivary:7.01

CAGE

uterus:4.04

placenta:4.00

prostate:3.95

ovary:3.99

testis:3.58

heart:3.75

muscle:3.88

esophagus:3.85

stomach:-

intestine:3.81

colon:3.88

liver/hepato:3.42

lung:3.78

bladder:3.93

kidney:3.73

pituitary:3.89

thyroid/parathyroid:3.57

adrenal gland:-

pancreas:3.78

breast:3.64

salivary:3.52

RNA-seq

uterus:-

placenta:-

prostate:3.93

ovary:4.84

testis:3.73

heart:3.20

muscle:3.66

esophagus:-

stomach:-

intestine:-

colon:3.85

liver/hepato:2.42

lung:3.18

bladder:-

kidney:3.43

pituitary:-

thyroid/parathyroid:3.90

adrenal gland:3.94

pancreas:-

breast:3.42

salivary:-

IDs

Refseq ID	NM_006565
Gene ID	10664
Unigene ID	Hs.368367
Probe set ID	202521_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000102974
GTEx ID	ENSG00000102974

Orthologous Gene

Mouse[2]	NM_181322
Rat[1]	NM_031824

Chromosomal Region

16q22.1 [67,596,310 - 67,673,086]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR015880	Zinc finger, C2H2-like
IPR007087	Zinc finger, C2H2-type

Gene Ontology (GO ID)

Biological Process

GO:0016568	chromatin modification
GO:0007059	chromosome segregation
GO:0006349	genetic imprinting
GO:0010216	maintenance of DNA methylation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0016584	nucleosome positioning
GO:0010628	positive regulation of gene expression
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0070602	regulation of centromeric sister chromatid cohesion
GO:0040029	regulation of gene expression, epigenetic
GO:0035065	regulation of histone acetylation
GO:0031060	regulation of histone methylation
GO:0040030	regulation of molecular function, epigenetic
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0000775	chromosome, centromeric region
GO:0000793	condensed chromosome
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0043035	chromatin insulator sequence binding
GO:0044212	DNA regulatory region binding
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0003714	transcription corepressor activity
GO:0003700	transcription factor activity
GO:0008270	zinc ion binding

CCCTC-binding factor (zinc finger protein)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function