polo-like kinase 4 (Drosophila)

Synonym

polo-like kinase 4 (Drosophila), Serine/threonine-protein kinase Sak, SAK, serine/threonine kinase 18, PLK4, Polo-like kinase 4, STK18, Serine/threonine-protein kinase PLK4, PLK-4, Serine/threonine-protein kinase 18

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:16.60

cerebellum:-

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:30

vein:-

lymphnode:40.40

peripheral blood:-

spleen:-

thymus:38.70

bone marrow:-

adipose:-

bone:-

skin:9.60

GeneChip

cerebrum:5.39

cerebellum:5.67

brain stem:5.51

corpus callosum/glia:5.45

pineal gland:-

peripheral nerve:5.39

spine:5.47

retina:-

eye:-

artery/aorta:5.33

vein:5.59

lymphnode:5.58

peripheral blood:-

spleen:5.42

thymus:7.28

bone marrow:6.85

adipose:5.45

bone:-

skin:5.48

CAGE

cerebrum:0.49

cerebellum:-

brain stem:0.74

corpus callosum/glia:0.18

pineal gland:0.82

peripheral nerve:-

spine:0.62

retina:-

eye:-

artery/aorta:0

vein:0.96

lymphnode:0.93

peripheral blood:-

spleen:0.95

thymus:2.51

bone marrow:-

adipose:0.46

bone:-

skin:-

RNA-seq

cerebrum:0.49

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.34

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:18.20

prostate:11.30

ovary:-

testis:134.10

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:4.90

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:27.90

salivary:-

GeneChip

uterus:5.61

placenta:5.90

prostate:5.29

ovary:5.41

testis:8.10

heart:5.35

muscle:5.36

esophagus:5.50

stomach:5.75

intestine:5.61

colon:5.51

liver/hepato:5.38

lung:5.39

bladder:-

kidney:5.36

pituitary:5.30

thyroid/parathyroid:5.21

adrenal gland:5.29

pancreas:5.60

breast:5.43

salivary:5.32

CAGE

uterus:0.54

placenta:1.35

prostate:0.66

ovary:0.72

testis:2.88

heart:0.37

muscle:0.17

esophagus:1.31

stomach:-

intestine:1.10

colon:1.37

liver/hepato:0.36

lung:0.59

bladder:0.33

kidney:0.62

pituitary:0.24

thyroid/parathyroid:0.41

adrenal gland:-

pancreas:0

breast:0.90

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.42

testis:2.90

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:0.00

bladder:-

kidney:0.16

pituitary:-

thyroid/parathyroid:0.32

adrenal gland:0.19

pancreas:-

breast:0.26

salivary:-

IDs

Refseq ID	NM_014264
Gene ID	10733
Unigene ID	Hs.172052
Probe set ID	204887_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000142731
GTEx ID	ENSG00000142731

Orthologous Gene

Mouse[3]	NM_011495
Rat[1]	NM_001107669

Chromosomal Region

4q28.2 [128,802,016 - 128,820,350]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

GO:0007099	centriole replication
GO:0000086	G2/M transition of mitotic cell cycle
GO:0000278	mitotic cell cycle
GO:0046601	positive regulation of centriole replication
GO:0006468	protein amino acid phosphorylation
GO:0060707	trophoblast giant cell differentiation

GO:0005814	centriole
GO:0005813	centrosome
GO:0032154	cleavage furrow
GO:0005829	cytosol
GO:0005730	nucleolus

GO:0005524	ATP binding
GO:0005515	protein binding
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity

polo-like kinase 4 (Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function