solute carrier family 27 (fatty acid transporter), member 2

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Synonym

HsT17226, FATP2, FACVL1, hFACVL1, Long-chain-fatty-acid--CoA ligase, Very-long-chain-fatty-acid-CoA ligase, Solute carrier family 27 member 2, VLACS, FATP-2, Fatty acid transport protein 2, SLC27A2, THCA-CoA ligase, VLCS, Fatty-acid-coenzyme A ligase, very long-chain 1, Very-long-chain acyl-CoA synthetase, ACSVL1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.90 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:54.70 spleen:- thymus:- bone marrow:19.70 adipose:- bone:- skin:9.60
GeneChip cerebrum:3.44 cerebellum:3.61 brain stem:3.33 corpus callosum/glia:3.20 pineal gland:- peripheral nerve:3.27 spine:3.22 retina:- eye:- artery/aorta:3.53 vein:3.40 lymphnode:3.50 peripheral blood:- spleen:3.17 thymus:3.19 bone marrow:4.39 adipose:3.95 bone:- skin:3.67
CAGE cerebrum:1.12 cerebellum:- brain stem:0.26 corpus callosum/glia:0.85 pineal gland:3.19 peripheral nerve:- spine:0.60 retina:- eye:- artery/aorta:2.08 vein:1.65 lymphnode:1.53 peripheral blood:- spleen:0.39 thymus:0.37 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:0.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.95 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:142.10 prostate:33.80 ovary:- testis:17.30 heart:- muscle:- esophagus:- stomach:- intestine:32.40 colon:135.70     liver/hepato:126.70        lung:34.20    bladder:- kidney:946.10 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:17.80 breast:- salivary:-
GeneChip uterus:3.24 placenta:5.27 prostate:4.64 ovary:4.41 testis:3.27 heart:3.26 muscle:3.32 esophagus:3.72 stomach:3.43 intestine:4.04 colon:4.79 liver/hepato:8.80 lung:3.45 bladder:- kidney:7.36 pituitary:5.22 thyroid/parathyroid:3.59 adrenal gland:3.77 pancreas:4.26 breast:4.23 salivary:3.10
CAGE uterus:0.57 placenta:3.14 prostate:1.26 ovary:1.16 testis:1.30 heart:0.40 muscle:0 esophagus:1.54 stomach:- intestine:2.90 colon:3.21     liver/hepato:6.19    lung:1.99 bladder:0.91 kidney:4.46 pituitary:3.56 thyroid/parathyroid:1.48 adrenal gland:- pancreas:3.02 breast:2.19 salivary:0
RNA-seq uterus:- placenta:- prostate:0.95 ovary:1.65 testis:2.00 heart:0.05 muscle:0 esophagus:- stomach:- intestine:- colon:1.10     liver/hepato:7.44        lung:1.95    bladder:- kidney:4.29 pituitary:- thyroid/parathyroid:1.76 adrenal gland:0.06 pancreas:- breast:0.11 salivary:-

Gene Information

IDs

Refseq ID NM_003645
Gene ID 11001
Unigene ID Hs.11729
Probe set ID 205769_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000140284
GTEx ID ENSG00000140284

Orthologous Gene

Mouse[1]  NM_011978
Rat [0]  

Chromosomal Region

15q21.2  [50,474,393  -  50,528,592]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
8889548
8939997
9671728
9730624
10198260
10471116
10479480
10640429
11980911
12477932
14702039
15161933
16756494
16781659
17998437
18781797
19056867
20178365
20965718
21768100
21890473
21906983
22028793
22939629
24113382
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006699  bile acid biosynthetic process
GO:0008206  bile acid metabolic process
GO:0044255  cellular lipid metabolic process
GO:0001561  fatty acid alpha-oxidation
GO:0006635  fatty acid beta-oxidation
GO:0001676  long-chain fatty acid metabolic process
GO:0042760  very-long-chain fatty acid catabolic process

Cellular Component

GO:0005788  endoplasmic reticulum lumen
GO:0005789  endoplasmic reticulum membrane
GO:0030176  integral to endoplasmic reticulum membrane
GO:0005779  integral to peroxisomal membrane
GO:0005739  mitochondrion
GO:0005778  peroxisomal membrane

Molecular Function

GO:0005524  ATP binding
GO:0019899  enzyme binding
GO:0015245  fatty acid transporter activity
GO:0004467  long-chain-fatty-acid-CoA ligase activity
GO:0050197  phytanate-CoA ligase activity
GO:0070251  pristanate-CoA ligase activity
GO:0005102  receptor binding
GO:0031957  very-long-chain-fatty-acid-CoA ligase activity