chitinase 3-like 1 (cartilage glycoprotein-39)

Synonym

GP-39, HCgp-39, Cartilage glycoprotein 39, chitinase 3-like 1 (cartilage glycoprotein-39), YKL-40, Chitinase-3-like protein 1 precursor, YYL-40, CHI3L1, 39 kDa synovial protein, HC-gp39, HCGP-3P, YKL40, GP39

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:56.90

cerebellum:37.80

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:30.70

spine:-

retina:118.60

eye:141

artery/aorta:-

vein:266.60

lymphnode:-

peripheral blood:15540.50

spleen:75.60

thymus:51.50

bone marrow:531.40

adipose:121

bone:2623

skin:144

GeneChip

cerebrum:6.50

cerebellum:4.82

brain stem:7.46

corpus callosum/glia:6

pineal gland:-

peripheral nerve:4.36

spine:7.13

retina:-

eye:-

artery/aorta:4.51

vein:4.79

lymphnode:5.42

peripheral blood:-

spleen:4.94

thymus:4.88

bone marrow:10.09

adipose:5.85

bone:-

skin:7.82

CAGE

cerebrum:4.16

cerebellum:-

brain stem:5.01

corpus callosum/glia:4.10

pineal gland:4.06

peripheral nerve:-

spine:5.19

retina:-

eye:-

artery/aorta:2.30

vein:2.16

lymphnode:4.27

peripheral blood:-

spleen:2.51

thymus:2.49

bone marrow:-

adipose:5.40

bone:-

skin:-

RNA-seq

cerebrum:3.94

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.75

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.73

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:29.10

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:342.80

stomach:-

intestine:-

colon:17

liver/hepato:10.60

lung:48.90

bladder:125.60

kidney:31.20

pituitary:463.90

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:-

breast:120.80

salivary:-

GeneChip

uterus:4.50

placenta:4.70

prostate:4.40

ovary:6.42

testis:3.82

heart:6.07

muscle:4.39

esophagus:5.10

stomach:5.38

intestine:4.87

colon:4.85

liver/hepato:7.11

lung:6.07

bladder:-

kidney:6.56

pituitary:5.28

thyroid/parathyroid:4.45

adrenal gland:4.29

pancreas:5.75

breast:7.93

salivary:5.24

CAGE

uterus:2.40

placenta:3.01

prostate:2.98

ovary:3.99

testis:2.73

heart:2.79

muscle:2.66

esophagus:2.99

stomach:-

intestine:0.69

colon:1.66

liver/hepato:8.07

lung:3.84

bladder:4.71

kidney:3.98

pituitary:4.97

thyroid/parathyroid:2.72

adrenal gland:-

pancreas:2.71

breast:4.03

salivary:3.30

RNA-seq

uterus:-

placenta:-

prostate:3.54

ovary:3.26

testis:5.05

heart:1.27

muscle:2.72

esophagus:-

stomach:-

intestine:-

colon:2.48

liver/hepato:8.76

lung:3.37

bladder:-

kidney:5.07

pituitary:-

thyroid/parathyroid:4.27

adrenal gland:3.58

pancreas:-

breast:4.73

salivary:-

IDs

Refseq ID	NM_001276
Gene ID	1116
Unigene ID	Hs.382202
Probe set ID	209395_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000133048
GTEx ID	ENSG00000133048

Orthologous Gene

Mouse[1]	NM_007695
Rat[1]	NM_053560

Chromosomal Region

1q32.1 [203,148,059 - 203,155,877]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR011583	Chitinase II
IPR017853	Glycoside hydrolase, catalytic core
IPR001223	Glycoside hydrolase, family 18, catalytic domain
IPR013781	Glycoside hydrolase, subgroup, catalytic core

Gene Ontology (GO ID)

Biological Process

GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0005975	carbohydrate metabolic process
GO:0051216	cartilage development
GO:0071356	cellular response to tumor necrosis factor
GO:0006032	chitin catabolic process
GO:0006954	inflammatory response
GO:0030324	lung development
GO:0045766	positive regulation of angiogenesis
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0010800	positive regulation of peptidyl-threonine phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0070555	response to interleukin-1
GO:0070741	response to interleukin-6
GO:0009612	response to mechanical stimulus
GO:0034612	response to tumor necrosis factor

Cellular Component

GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005615	extracellular space
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0008061	chitin binding
GO:0004568	chitinase activity
GO:0005201	extracellular matrix structural constituent

chitinase 3-like 1 (cartilage glycoprotein-39)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function