calcium binding protein P22

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Synonym

calcium binding protein P22, SLC9A1BP, CHP

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:45 cerebellum:50.40 brain stem:- corpus callosum/glia:58.30 pineal gland:148.30 peripheral nerve:122.70 spine:112.30 retina:237.30 eye:41.10 artery/aorta:30 vein:199.90 lymphnode:40.40 peripheral blood:54.70 spleen:18.90 thymus:103.10 bone marrow:196.80 adipose:40.30 bone:76.80 skin:91.20
GeneChip cerebrum:8.74 cerebellum:8.23 brain stem:9.17 corpus callosum/glia:8.52 pineal gland:- peripheral nerve:9.26 spine:8.87 retina:- eye:- artery/aorta:8.51 vein:8.67 lymphnode:8.53 peripheral blood:- spleen:8.10 thymus:8.03 bone marrow:8.75 adipose:9.56 bone:- skin:9.32
CAGE cerebrum:4.68 cerebellum:- brain stem:4.87 corpus callosum/glia:4.77 pineal gland:4.47 peripheral nerve:- spine:4.82 retina:- eye:- artery/aorta:4.63 vein:4.68 lymphnode:4.69 peripheral blood:- spleen:4.34 thymus:4.02 bone marrow:- adipose:5.47 bone:- skin:-
RNA-seq cerebrum:5.16 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.74 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:36.40 prostate:78.90 ovary:223.60 testis:26 heart:76.60 muscle:20.10 esophagus:- stomach:85 intestine:32.40 colon:144.20     liver/hepato:52.80        lung:73.30    bladder:125.60 kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:- breast:148.70 salivary:328.40
GeneChip uterus:8.75 placenta:7.96 prostate:9.24 ovary:8.55 testis:7.28 heart:8.70 muscle:8.91 esophagus:9.86 stomach:9.24 intestine:9.24 colon:9.41 liver/hepato:9.89 lung:9.19 bladder:- kidney:9.33 pituitary:8.36 thyroid/parathyroid:9.13 adrenal gland:9.34 pancreas:9.67 breast:9.11 salivary:9.13
CAGE uterus:4.55 placenta:4.21 prostate:4.57 ovary:4.43 testis:4.00 heart:4.97 muscle:5.35 esophagus:5.16 stomach:- intestine:5.76 colon:5.33     liver/hepato:5.94    lung:5.45 bladder:4.89 kidney:5.29 pituitary:4.50 thyroid/parathyroid:4.88 adrenal gland:- pancreas:5.13 breast:5.31 salivary:5.05
RNA-seq uterus:- placenta:- prostate:5.13 ovary:4.80 testis:4.65 heart:4.83 muscle:6.13 esophagus:- stomach:- intestine:- colon:5.28     liver/hepato:6.71        lung:5.77    bladder:- kidney:5.82 pituitary:- thyroid/parathyroid:5.23 adrenal gland:4.24 pancreas:- breast:6.13 salivary:-

Gene Information

IDs

Refseq ID NM_007236
Gene ID 11261
Unigene ID Hs.406234
Probe set ID 214665_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000187446
GTEx ID ENSG00000187446

Orthologous Gene

Mouse[3]  NM_019769
Rat [0]  

Chromosomal Region

15q15.1  [41,523,342  -  41,574,088]

Gene Family (Interpro ID)

IPR002048  Calcium-binding EF-hand
IPR018249  EF-HAND 2

Link to Pubmed  (Pubmed ID)

7829101
8626580
8901634
10593895
11350981
11481038
12204119
12226101
12477932
12576672
14702039
15035633
15312048
15489334
15987692
16169070
16341674
16511206
17050540
18029348
18628988
18815128
19056867
19165527
19322201
20720019
21085126
21139048
21906983
22190034
23000965
23128233

Gene Ontology  (GO ID)

Biological Process

GO:0017156  calcium ion-dependent exocytosis
GO:0071468  cellular response to acidity
GO:0031122  cytoplasmic microtubule organization
GO:0022406  membrane docking
GO:0001578  microtubule bundle formation
GO:0070885  negative regulation of calcineurin-NFAT signaling pathway
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0010923  negative regulation of phosphatase activity
GO:0031953  negative regulation of protein amino acid autophosphorylation
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0042308  negative regulation of protein import into nucleus
GO:0006469  negative regulation of protein kinase activity
GO:0031397  negative regulation of protein ubiquitination
GO:0060050  positive regulation of protein amino acid glycosylation
GO:0051222  positive regulation of protein transport
GO:0032417  positive regulation of sodium:hydrogen antiporter activity
GO:0006813  potassium ion transport
GO:0006611  protein export from nucleus
GO:0051259  protein oligomerization
GO:0050821  protein stabilization
GO:0051453  regulation of intracellular pH
GO:0007264  small GTPase mediated signal transduction
GO:0045056  transcytosis

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005793  ER-Golgi intermediate compartment
GO:0000139  Golgi membrane
GO:0015630  microtubule cytoskeleton
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0030133  transport vesicle

Molecular Function

GO:0005509  calcium ion binding
GO:0048306  calcium-dependent protein binding
GO:0019900  kinase binding
GO:0008017  microtubule binding
GO:0015459  potassium channel regulator activity
GO:0005515  protein binding
GO:0004860  protein kinase inhibitor activity
GO:0005215  transporter activity