phosphoinositide-3-kinase interacting protein 1

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Synonym

hHGFL(S), HGFL, HGFL gene, MGC17330

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:177.80 cerebellum:125.90 brain stem:- corpus callosum/glia:320.80 pineal gland:- peripheral nerve:122.70 spine:336.90 retina:- eye:82.30 artery/aorta:30 vein:66.60 lymphnode:171.90 peripheral blood:510.10 spleen:699.50 thymus:605.50 bone marrow:78.70 adipose:80.70 bone:204.70 skin:96
GeneChip cerebrum:7.87 cerebellum:8.06 brain stem:8 corpus callosum/glia:8.30 pineal gland:- peripheral nerve:8.28 spine:8.07 retina:- eye:- artery/aorta:7.60 vein:7.66 lymphnode:8.79 peripheral blood:- spleen:8.65 thymus:8.33 bone marrow:7.23 adipose:8.13 bone:- skin:7.53
CAGE cerebrum:3.74 cerebellum:- brain stem:3.93 corpus callosum/glia:4.08 pineal gland:3.00 peripheral nerve:- spine:3.90 retina:- eye:- artery/aorta:3.86 vein:4.49 lymphnode:4.85 peripheral blood:- spleen:4.17 thymus:4.44 bone marrow:- adipose:4.07 bone:- skin:-
RNA-seq cerebrum:1.96 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.59 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.72 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:164 placenta:105.60 prostate:214 ovary:74.50 testis:64.90 heart:51.10 muscle:40.20 esophagus:- stomach:85 intestine:259.20 colon:50.90     liver/hepato:-        lung:166.20    bladder:376.80 kidney:83.20 pituitary:116 thyroid/parathyroid:163.70 adrenal gland:50.80 pancreas:17.80 breast:83.60 salivary:-
GeneChip uterus:7.42 placenta:7.08 prostate:7.51 ovary:7.88 testis:7.61 heart:7.61 muscle:7.22 esophagus:7.31 stomach:7.64 intestine:7.47 colon:7.93 liver/hepato:6.84 lung:8.32 bladder:- kidney:7.57 pituitary:7.47 thyroid/parathyroid:8.56 adrenal gland:7.69 pancreas:7.37 breast:8.01 salivary:7.65
CAGE uterus:3.60 placenta:3.08 prostate:3.65 ovary:3.09 testis:3.81 heart:3.11 muscle:3.36 esophagus:3.49 stomach:- intestine:3.35 colon:3.45     liver/hepato:1.90    lung:4.07 bladder:3.97 kidney:2.98 pituitary:2.23 thyroid/parathyroid:4.23 adrenal gland:- pancreas:2.18 breast:3.90 salivary:3.53
RNA-seq uterus:- placenta:- prostate:0.54 ovary:0.09 testis:1.31 heart:1.27 muscle:1.89 esophagus:- stomach:- intestine:- colon:0.85     liver/hepato:0.03        lung:3.45    bladder:- kidney:0.46 pituitary:- thyroid/parathyroid:1.20 adrenal gland:2.60 pancreas:- breast:1.04 salivary:-

Gene Information

IDs

Refseq ID NM_001135911
Gene ID 113791
Unigene ID Hs.26670
Probe set ID 221756_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000100100
GTEx ID ENSG00000100100

Orthologous Gene

Mouse[1]  NM_178149
Rat [0]  

Chromosomal Region

22q12.2  [31,677,579  -  31,688,520]

Gene Family (Interpro ID)

IPR000001  Kringle
IPR013806  Kringle-like fold

Link to Pubmed  (Pubmed ID)

8889548
10591208
12477932
12529303
14702039
15340161
15461802
15489334
16303743
17475214
18632611
19088825
22706993

Gene Ontology  (GO ID)

Biological Process

GO:0043553  negative regulation of phosphoinositide 3-kinase activity
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade

Cellular Component

GO:0016021  integral to membrane