ArfGAP with GTPase domain, ankyrin repeat and PH domain 4

 jump to detail

Synonym

centaurin, gamma-like family, member 1, Em:AC012044.1, MRIP2, CTGLF1, CTGLF5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.99 cerebellum:8.22 brain stem:7.90 corpus callosum/glia:8.20 pineal gland:- peripheral nerve:7.78 spine:7.83 retina:- eye:- artery/aorta:7.98 vein:7.70 lymphnode:8.34 peripheral blood:- spleen:8.19 thymus:7.85 bone marrow:7.61 adipose:8.15 bone:- skin:7.75
CAGE nodata
RNA-seq cerebrum:1.14 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.88 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.74 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.97 placenta:7.45 prostate:8.11 ovary:7.95 testis:8.96 heart:7.68 muscle:7.43 esophagus:7.96 stomach:8.42 intestine:8.05 colon:7.57 liver/hepato:8.47 lung:8 bladder:- kidney:8.15 pituitary:8.59 thyroid/parathyroid:8.27 adrenal gland:8.45 pancreas:7.12 breast:8.15 salivary:7.89
CAGE nodata
RNA-seq uterus:- placenta:- prostate:1.67 ovary:1.71 testis:1.69 heart:0.61 muscle:0.34 esophagus:- stomach:- intestine:- colon:0.84     liver/hepato:0.96        lung:1.13    bladder:- kidney:1.54 pituitary:- thyroid/parathyroid:1.24 adrenal gland:2.21 pancreas:- breast:1.67 salivary:-

Gene Information

IDs

Refseq ID NM_133446
Gene ID 119016
Unigene ID -
Probe set ID 221971_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000188234
GTEx ID ENSG00000188234

Orthologous Gene

Mouse[2]  NM_001037136, NM_178119
Rat [0]  

Chromosomal Region

10q11.22  [46,321,042  -  46,349,323]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

12477932
15164054
20139978
21248752
22990118

Gene Ontology  (GO ID)

Biological Process

GO:0032312  regulation of ARF GTPase activity

Molecular Function

GO:0008060  ARF GTPase activator activity
GO:0005543  phospholipid binding
GO:0008270  zinc ion binding