chemokine (C-C motif) receptor 7

Synonym

CMKBR7, CCR7, C-C chemokine receptor type 7 precursor, CDw197, CD197 antigen, MIP-3 beta receptor, EBI1, C-C CKR-7, CCR-7, BLR2, chemokine (C-C motif) receptor 7, EBV-induced G-protein coupled receptor 1, EVI1, CC-CKR-7, CD197

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:5.90

artery/aorta:-

vein:-

lymphnode:70.80

peripheral blood:838.10

spleen:189.10

thymus:141.70

bone marrow:39.40

adipose:-

bone:51.20

skin:211.20

GeneChip

cerebrum:3.59

cerebellum:3.91

brain stem:3.69

corpus callosum/glia:3.53

pineal gland:-

peripheral nerve:3.76

spine:3.67

retina:-

eye:-

artery/aorta:3.76

vein:4.13

lymphnode:7.72

peripheral blood:-

spleen:7.13

thymus:7.21

bone marrow:5.16

adipose:4.82

bone:-

skin:4.06

CAGE

cerebrum:0.01

cerebellum:-

brain stem:0.03

corpus callosum/glia:0.18

pineal gland:0

peripheral nerve:-

spine:0.13

retina:-

eye:-

artery/aorta:0.69

vein:4.37

lymphnode:5.08

peripheral blood:-

spleen:3.77

thymus:4.63

bone marrow:-

adipose:0.26

bone:-

skin:-

RNA-seq

cerebrum:0.06

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.86

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.46

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:3.60

prostate:-

ovary:-

testis:8.70

heart:-

muscle:-

esophagus:-

stomach:21.20

intestine:32.40

colon:25.40

liver/hepato:-

lung:9.80

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:44.50

breast:-

salivary:-

GeneChip

uterus:3.70

placenta:3.96

prostate:3.55

ovary:3.68

testis:3.66

heart:3.77

muscle:3.74

esophagus:3.87

stomach:4.59

intestine:4.34

colon:5.17

liver/hepato:3.75

lung:4.73

bladder:-

kidney:3.60

pituitary:3.51

thyroid/parathyroid:4.06

adrenal gland:3.58

pancreas:4.29

breast:4.30

salivary:4.01

CAGE

uterus:0.44

placenta:0.95

prostate:0.58

ovary:0.26

testis:0.21

heart:0.25

muscle:0

esophagus:1.39

stomach:-

intestine:1.05

colon:1.49

liver/hepato:0.14

lung:1.92

bladder:1.83

kidney:1.19

pituitary:0

thyroid/parathyroid:0.41

adrenal gland:-

pancreas:0

breast:0

salivary:1.82

RNA-seq

uterus:-

placenta:-

prostate:0.53

ovary:0.55

testis:0.25

heart:0.02

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.40

liver/hepato:0.35

lung:0.88

bladder:-

kidney:0.31

pituitary:-

thyroid/parathyroid:0.40

adrenal gland:4.69

pancreas:-

breast:0.46

salivary:-

IDs

Refseq ID	NM_001838
Gene ID	1236
Unigene ID	Hs.370036
Probe set ID	206337_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000126353
GTEx ID	ENSG00000126353

Orthologous Gene

Mouse[1]	NM_007719
Rat[1]	NM_199489

Chromosomal Region

17q21.2 [38,710,021 - 38,721,724]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR005383	C-C chemokine receptor, type 11
IPR001718	C-C chemokine receptor, type 7
IPR001277	C-X-C chemokine receptor, type 4
IPR000355	Chemokine receptor
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0032862	activation of Rho GTPase activity
GO:0002407	dendritic cell chemotaxis
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0001768	establishment of T cell polarity
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0002408	myeloid dendritic cell chemotaxis
GO:0045060	negative thymic T cell selection
GO:0030838	positive regulation of actin filament polymerization
GO:0045785	positive regulation of cell adhesion
GO:0001954	positive regulation of cell-matrix adhesion
GO:0002606	positive regulation of dendritic cell antigen processing and presentation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0051491	positive regulation of filopodium assembly
GO:0002922	positive regulation of humoral immune response
GO:0002885	positive regulation of hypersensitivity
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032735	positive regulation of interleukin-12 production
GO:0046330	positive regulation of JNK cascade
GO:0090023	positive regulation of neutrophil chemotaxis
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0045860	positive regulation of protein kinase activity
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0031274	positive regulation of pseudopodium assembly
GO:0050862	positive regulation of T cell receptor signaling pathway
GO:0032649	regulation of interferon-gamma production
GO:0050706	regulation of interleukin-1 beta secretion
GO:0051209	release of sequestered calcium ion into cytosol
GO:0032496	response to lipopolysaccharide
GO:0034695	response to prostaglandin E stimulus
GO:0031529	ruffle organization

Cellular Component

GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0005622	intracellular
GO:0005886	plasma membrane

Molecular Function

GO:0016493	C-C chemokine receptor activity
GO:0004930	G-protein coupled receptor activity

chemokine (C-C motif) receptor 7

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function