chemokine (C-X3-C motif) receptor 1

Synonym

CMKDR1, chemokine (C-X3-C) receptor 1, GPR13, CMK-BRL-1, G-protein coupled receptor 13, V28, Fractalkine receptor, chemokine (C-X3-C motif) receptor 1, GPRV28, CMKBRL1, Beta chemokine receptor-like 1, CX3CR1, C-X3-C CKR-1, CCRL1, CX3C chemokine receptor 1, CMKBLR1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:85.30

cerebellum:75.60

brain stem:-

corpus callosum/glia:58.30

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:54.70

spleen:75.60

thymus:12.90

bone marrow:-

adipose:-

bone:-

skin:9.60

GeneChip

cerebrum:7.64

cerebellum:5.29

brain stem:8.26

corpus callosum/glia:9.19

pineal gland:-

peripheral nerve:8.42

spine:9.49

retina:-

eye:-

artery/aorta:4.84

vein:5.64

lymphnode:5.38

peripheral blood:-

spleen:7.54

thymus:4.54

bone marrow:5.94

adipose:4.95

bone:-

skin:4.91

CAGE

cerebrum:3.18

cerebellum:-

brain stem:4.52

corpus callosum/glia:5.45

pineal gland:1.64

peripheral nerve:-

spine:3.78

retina:-

eye:-

artery/aorta:1.82

vein:1.10

lymphnode:2.04

peripheral blood:-

spleen:2.55

thymus:1.87

bone marrow:-

adipose:1.25

bone:-

skin:-

RNA-seq

cerebrum:2.37

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.47

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.27

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:21.90

prostate:78.90

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:19.60

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:26.70

breast:18.60

salivary:-

GeneChip

uterus:5.53

placenta:5.18

prostate:5.72

ovary:6.13

testis:4.40

heart:4.51

muscle:5.25

esophagus:4.47

stomach:4.51

intestine:5.02

colon:4.80

liver/hepato:5.35

lung:6.14

bladder:-

kidney:4.73

pituitary:5.48

thyroid/parathyroid:4.97

adrenal gland:5.13

pancreas:4.63

breast:6.10

salivary:6.46

CAGE

uterus:2.19

placenta:2.64

prostate:3.06

ovary:2.02

testis:1.27

heart:1.18

muscle:1.21

esophagus:0.82

stomach:-

intestine:0.77

colon:0.79

liver/hepato:1.57

lung:2.01

bladder:1.15

kidney:1.40

pituitary:1.00

thyroid/parathyroid:0.53

adrenal gland:-

pancreas:1.87

breast:0.90

salivary:2.72

RNA-seq

uterus:-

placenta:-

prostate:0.62

ovary:1.60

testis:1.04

heart:0.34

muscle:0.70

esophagus:-

stomach:-

intestine:-

colon:0.05

liver/hepato:0.22

lung:0.60

bladder:-

kidney:0.49

pituitary:-

thyroid/parathyroid:0.23

adrenal gland:0.78

pancreas:-

breast:1.23

salivary:-

IDs

Refseq ID	NM_001337
Gene ID	1524
Unigene ID	Hs.78913
Probe set ID	205898_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000168329
GTEx ID	ENSG00000168329

Orthologous Gene

Mouse[2]	NM_009987
Rat [0]

Chromosomal Region

3p22.2 [39,304,985 - 39,323,226]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR001277	C-X-C chemokine receptor, type 4
IPR000355	Chemokine receptor
IPR005387	CX3C Fractalkine chemokine receptor
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007155	cell adhesion
GO:0006968	cellular defense response
GO:0071222	cellular response to lipopolysaccharide
GO:0021795	cerebral cortex cell migration
GO:0070098	chemokine-mediated signaling pathway
GO:0006935	chemotaxis
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0048246	macrophage chemotaxis
GO:0002282	microglial cell activation during immune response
GO:0016525	negative regulation of angiogenesis
GO:0043066	negative regulation of apoptosis
GO:0030336	negative regulation of cell migration
GO:0045766	positive regulation of angiogenesis
GO:0009611	response to wounding
GO:0019048	virus-host interaction

Cellular Component

GO:0032809	cell soma membrane
GO:0005887	integral to plasma membrane
GO:0043005	neuron projection
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0016495	C-X3-C chemokine receptor activity
GO:0004950	chemokine receptor activity
GO:0005515	protein binding

chemokine (C-X3-C motif) receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function