adrenergic, beta-1-, receptor

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Synonym

Beta-1 adrenoceptor, Beta-1 adrenergic receptor, ADRB1, ADRB1R, RHR, Beta-1 adrenoreceptor, adrenergic, beta-1-, receptor, B1AR, BETA1AR

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:593.40 peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.69 cerebellum:3.61 brain stem:3.64 corpus callosum/glia:3.44 pineal gland:- peripheral nerve:3.27 spine:3.34 retina:- eye:- artery/aorta:3.46 vein:3.64 lymphnode:3.39 peripheral blood:- spleen:3.20 thymus:3.12 bone marrow:3.34 adipose:3.64 bone:- skin:3.71
CAGE cerebrum:3.09 cerebellum:- brain stem:1.97 corpus callosum/glia:1.92 pineal gland:6.32 peripheral nerve:- spine:2.13 retina:- eye:- artery/aorta:1.85 vein:2.60 lymphnode:1.19 peripheral blood:- spleen:1.79 thymus:0.57 bone marrow:- adipose:2.54 bone:- skin:-
RNA-seq cerebrum:2.39 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.27 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.97 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:21.90 prostate:- ovary:- testis:4.30 heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.26 placenta:4.70 prostate:3.54 ovary:3.40 testis:3.26 heart:4.28 muscle:3.55 esophagus:3.28 stomach:3.29 intestine:3.48 colon:3.40 liver/hepato:3.31 lung:4.26 bladder:- kidney:3.38 pituitary:3.30 thyroid/parathyroid:3.13 adrenal gland:3.23 pancreas:3.85 breast:3.31 salivary:3.57
CAGE uterus:0.44 placenta:4.98 prostate:2.98 ovary:0.47 testis:0.66 heart:4.56 muscle:0.34 esophagus:1.44 stomach:- intestine:1.77 colon:1.74     liver/hepato:0.46    lung:4.15 bladder:1.45 kidney:1.40 pituitary:0.58 thyroid/parathyroid:0.64 adrenal gland:- pancreas:1.74 breast:3.22 salivary:3.22
RNA-seq uterus:- placenta:- prostate:1.22 ovary:0.09 testis:0.29 heart:3.20 muscle:0.13 esophagus:- stomach:- intestine:- colon:0.76     liver/hepato:0.12        lung:2.74    bladder:- kidney:0.72 pituitary:- thyroid/parathyroid:0.35 adrenal gland:0.37 pancreas:- breast:3.03 salivary:-

IDs

Refseq ID NM_000684
Gene ID 153
Unigene ID Hs.99913
Probe set ID 208214_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000043591
GTEx ID ENSG00000043591

Orthologous Gene

Mouse[1]  NM_007419
Rat[1]  NM_012701

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

2154750
2465637
2536864
2825170
6305985
7583452
8892658
9843378
10212248
10477438
10535961
10794544
10862778
10995758
11052857
11140838
11337934
11447084
11526121
11700307
11753577
11854867
11942593
12023679
12029453
12032746
12036966
12069593
12090746
12106601
12140284
12184796
12197595
12244098
12270132
12374873
12391161
12422153
12455717
12519093
12529373
12544508
12643891
12709726
12724327
12815745
12844134
12847069
12851615
12921807
14502278
14534524
14553962
14734649
14990580
15055253
15079793
15086532
15123239
15212591
15212839
15237695
15312808
15331590
15342173
15358775
15388645
15452121
15464701
15479221
15542284
15564877
15685248
15719258
15735607
15824464
15833937
15861037
15864115
15917856
15932670
16122377
16153393
16187973
16189366
16210433
16227135
16287427
16315032
16316992
16325708
16402084
16421173
16485781
16487965
16500896
16534528
16648137
16728691
16760361
16765375
16785856
16815314
16844790
16907703
16914520
16940053
16946993
16997396
17023080
17118120
17217681
17223428
17270896
17329986
17334644
17335470
17339538
17345787
17383306
17463065
17496726
17512307
17541557
17585213
17591269
17635183
17644825
17667029
17680533
17845930
17893006
17919552
17998459
18059082
18075464
18155231
18158268
18193079
18209576
18219297
18239290
18240029
18253135
18298953
18308161
18311486
18323523
18331634
18346809
18403719
18413308
18413560
18429752
18452871
18479335
18534365
18540901
18596718
18615004
18622236
18625943
18679149
18702937
18702968
18754404
18772317
18773997
18776959
18787115
18794726
18797399
18936436
18937294
18947427
18996102
19010176
19033826
19036891
19037712
19056576
19073901
19086053
19094446
19167638
19301767
19378229
19477404
19509284
19515093
19538012
19542315
19553224
19576569
19578796
19621046
19623647
19628119
19673943
19743955
19745105
19779464
19842931
19845516
19883298
19913121
19956635
20023040
20044737
20079238
20116105
20123316
20129829
20144152
20185488
20203292
20235788
20300048
20352314
20374546
20384459
20414837
20426789
20443839
20459474
20468064
20470286
20537417
20538960
20581797
20587416
20602615
20625396
20628086
20643254
20693591
20705341
20726983
20731869
20803192
20821015
20831043
20948559
20952631
21034538
21044781
21059181
21238583
21305273
21311897
21375401
21422729
21464135
21516734
21527343
21553224
21573230
21599570
21626217
21807569
21847570
21878665
21909110
22192668
22253823
22299391
22306453
22340652
22378779
22388998
22447021
22495925
22617224
22703382
22723743
22742717
22811559
22815685
22994654
23060133
23065660
23114278
23115322
23202124
23223178
23257656
23261005
23266473
23271137
23275278
23318885
23351074
23370410
23533220
23588958
23729404
24121510
24151242
24324269
24332148
24334028
24342311
24437165

Gene Ontology  (GO ID)

Biological Process

GO:0007190  activation of adenylate cyclase activity
GO:0007568  aging
GO:0006915  apoptosis
GO:0050873  brown fat cell differentiation
GO:0002024  diet induced thermogenesis
GO:0042596  fear response
GO:0005980  glycogen catabolic process
GO:0031649  heat generation
GO:0055088  lipid homeostasis
GO:0007613  memory
GO:0040015  negative regulation of multicellular organism growth
GO:0045986  negative regulation of smooth muscle contraction
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0043950  positive regulation of cAMP-mediated signaling
GO:0001996  positive regulation of heart rate by epinephrine-norepinephrine
GO:0032320  positive regulation of Ras GTPase activity
GO:0046878  positive regulation of saliva secretion
GO:0003084  positive regulation of systemic arterial blood pressure
GO:0003061  positive regulation of the force of heart contraction by norepinephrine
GO:0033365  protein localization in organelle
GO:0051924  regulation of calcium ion transport
GO:0060080  regulation of inhibitory postsynaptic membrane potential
GO:0009409  response to cold
GO:0007266  Rho protein signal transduction
GO:0019233  sensory perception of pain
GO:0002025  vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0042060  wound healing

Cellular Component

GO:0005737  cytoplasm
GO:0005887  integral to plasma membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0031694  alpha-2A adrenergic receptor binding
GO:0004939  beta-adrenergic receptor activity
GO:0004940  beta1-adrenergic receptor activity
GO:0035240  dopamine binding
GO:0008144  drug binding
GO:0051379  epinephrine binding
GO:0051380  norepinephrine binding
GO:0030165  PDZ domain binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0005088  Ras guanyl-nucleotide exchange factor activity
GO:0005057  receptor signaling protein activity