iroquois homeobox 2

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Synonym

iroquois homeobox protein 2, Iroquois-class homeodomain protein IRX-2, Iroquois homeobox protein 2, IRXA2, IRX2, Homeodomain protein IRXA2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip nodata
CAGE cerebrum:0.90 cerebellum:- brain stem:3.17 corpus callosum/glia:0.88 pineal gland:0.83 peripheral nerve:- spine:2.32 retina:- eye:- artery/aorta:2.08 vein:1.17 lymphnode:0.96 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:1.71 bone:- skin:-
RNA-seq cerebrum:0.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.60 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.71 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:18.20 prostate:11.30 ovary:- testis:8.70 heart:51.10 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:63.50    bladder:- kidney:166.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:160 breast:18.60 salivary:-
GeneChip nodata
CAGE uterus:0.32 placenta:2.78 prostate:2.21 ovary:0.14 testis:1.88 heart:0.90 muscle:0.24 esophagus:1.64 stomach:- intestine:0 colon:0.34     liver/hepato:0.14    lung:4.13 bladder:0.40 kidney:3.18 pituitary:1.18 thyroid/parathyroid:1.30 adrenal gland:- pancreas:0 breast:3.90 salivary:3.82
RNA-seq uterus:- placenta:- prostate:0.56 ovary:0.02 testis:1.78 heart:1.58 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.08     liver/hepato:0.00        lung:2.34    bladder:- kidney:3.11 pituitary:- thyroid/parathyroid:0.67 adrenal gland:0.10 pancreas:- breast:2.33 salivary:-

Gene Information

IDs

Refseq ID NM_033267
Gene ID 153572
Unigene ID Hs.282089
Probe set ID -
Ensembl ID ENSG00000170561
GTEx ID ENSG00000170561

Orthologous Gene

Mouse[1]  NM_010574
Rat[1]  NM_001039505

Chromosomal Region

5p15.33  [2,745,959  -  2,752,969]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

8889548
10370142
11435706
12477932
15133517
16752383
18421076
22210879

Gene Ontology  (GO ID)

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity