cylindromatosis (turban tumor syndrome)

Synonym

USPL2, FLJ31664, CYLDI, CYLD, Ubiquitin thioesterase CYLD, CDMT, cylindromatosis (turban tumor syndrome), FLJ20180, KIAA0849, HSPC057, Ubiquitin-specific-processing protease CYLD, Deubiquitinating enzyme CYLD, CYLD1, EAC

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:62.80

cerebellum:37.80

brain stem:-

corpus callosum/glia:116.60

pineal gland:148.30

peripheral nerve:30.70

spine:-

retina:-

eye:76.40

artery/aorta:119.90

vein:-

lymphnode:151.70

peripheral blood:145.70

spleen:37.80

thymus:38.70

bone marrow:59

adipose:-

bone:25.60

skin:43.20

GeneChip

cerebrum:7.63

cerebellum:7.17

brain stem:7.68

corpus callosum/glia:7.46

pineal gland:-

peripheral nerve:6.71

spine:7.30

retina:-

eye:-

artery/aorta:6.45

vein:6.79

lymphnode:7.61

peripheral blood:-

spleen:7.48

thymus:7.08

bone marrow:6.23

adipose:6.48

bone:-

skin:6.51

CAGE

cerebrum:3.36

cerebellum:-

brain stem:3.24

corpus callosum/glia:3.36

pineal gland:4.04

peripheral nerve:-

spine:3.33

retina:-

eye:-

artery/aorta:3.40

vein:2.94

lymphnode:3.47

peripheral blood:-

spleen:3.27

thymus:3.02

bone marrow:-

adipose:2.64

bone:-

skin:-

RNA-seq

cerebrum:3.61

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.22

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.68

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:100.20

placenta:32.80

prostate:78.90

ovary:149.10

testis:147.10

heart:102.20

muscle:-

esophagus:-

stomach:21.20

intestine:-

colon:25.40

liver/hepato:31.70

lung:48.90

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:124.50

breast:18.60

salivary:-

GeneChip

uterus:6.41

placenta:6.02

prostate:6.66

ovary:6.48

testis:5.27

heart:6.07

muscle:6.68

esophagus:6.38

stomach:6.29

intestine:5.98

colon:5.79

liver/hepato:6.19

lung:6.51

bladder:-

kidney:5.78

pituitary:7.42

thyroid/parathyroid:7.01

adrenal gland:6.67

pancreas:5.30

breast:6.75

salivary:6.13

CAGE

uterus:3.01

placenta:2.36

prostate:2.87

ovary:2.43

testis:3.10

heart:2.75

muscle:2.97

esophagus:2.87

stomach:-

intestine:2.64

colon:2.59

liver/hepato:2.47

lung:3.01

bladder:2.73

kidney:2.30

pituitary:3.72

thyroid/parathyroid:2.98

adrenal gland:-

pancreas:2.76

breast:2.53

salivary:2.97

RNA-seq

uterus:-

placenta:-

prostate:2.81

ovary:2.57

testis:3.07

heart:2.14

muscle:3.02

esophagus:-

stomach:-

intestine:-

colon:1.13

liver/hepato:1.85

lung:1.64

bladder:-

kidney:1.81

pituitary:-

thyroid/parathyroid:2.54

adrenal gland:2.55

pancreas:-

breast:2.26

salivary:-

IDs

Refseq ID	NM_001042355
Gene ID	1540
Unigene ID	Hs.578973
Probe set ID	213295_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000083799
GTEx ID	ENSG00000083799

Orthologous Gene

Mouse[4]	NM_001128169, NM_001128170, NM_001128171, NM_173369
Rat[2]	NM_001017380, NM_001128170, NM_001128171, NM_173369

Chromosomal Region

16q12.1 [50,775,961 - 50,835,846]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007049	cell cycle
GO:0045087	innate immune response
GO:0042347	negative regulation of NF-kappaB import into nucleus
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0032480	negative regulation of type I interferon production
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway
GO:0070536	protein K63-linked deubiquitination
GO:0070507	regulation of microtubule cytoskeleton organization
GO:0007346	regulation of mitotic cell cycle
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0016055	Wnt receptor signaling pathway

Cellular Component

GO:0005881	cytoplasmic microtubule
GO:0005829	cytosol
GO:0031234	extrinsic to internal side of plasma membrane
GO:0030496	midbody
GO:0048471	perinuclear region of cytoplasm

Molecular Function

GO:0070064	proline-rich region binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0004221	ubiquitin thiolesterase activity
GO:0004843	ubiquitin-specific protease activity
GO:0008270	zinc ion binding

cylindromatosis (turban tumor syndrome)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function