dopamine beta-hydroxylase (dopamine beta-monooxygenase)

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Synonym

DBH, DBM, Dopamine beta-monooxygenase, Dopamine beta-hydroxylase precursor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:3.60

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:92

spine:1123

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:10.10

peripheral blood:-

spleen:-

thymus:12.90

bone marrow:-

adipose:-

bone:-

skin:4.80

GeneChip

cerebrum:4.91

cerebellum:5.08

brain stem:4.87

corpus callosum/glia:4.94

pineal gland:-

peripheral nerve:4.71

spine:4.69

retina:-

eye:-

artery/aorta:5.06

vein:5.26

lymphnode:5.08

peripheral blood:-

spleen:4.58

thymus:4.62

bone marrow:4.97

adipose:4.81

bone:-

skin:4.86

CAGE

cerebrum:0

cerebellum:-

brain stem:0.70

corpus callosum/glia:1.11

pineal gland:0

peripheral nerve:-

spine:0.58

retina:-

eye:-

artery/aorta:0.47

vein:2.27

lymphnode:0

peripheral blood:-

spleen:0.25

thymus:0.06

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.27

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.78

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.01

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.66

placenta:4.72

prostate:4.43

ovary:4.82

testis:4.51

heart:4.81

muscle:4.90

esophagus:4.81

stomach:4.64

intestine:4.82

colon:4.86

liver/hepato:5.69

lung:4.84

bladder:-

kidney:4.79

pituitary:5.06

thyroid/parathyroid:4.85

adrenal gland:6.40

pancreas:5.57

breast:4.51

salivary:4.81

CAGE

uterus:0.19

placenta:0

prostate:0.58

ovary:0

testis:0

heart:0.08

muscle:0

esophagus:0

stomach:-

intestine:0

colon:0

liver/hepato:3.41

lung:0

bladder:0.58

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0.58

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.68

ovary:0.23

testis:0.49

heart:0.01

muscle:0.07

esophagus:-

stomach:-

intestine:-

colon:0.02

liver/hepato:2.64

lung:0.11

bladder:-

kidney:0.17

pituitary:-

thyroid/parathyroid:0.15

adrenal gland:0.30

pancreas:-

breast:0.04

salivary:-

IDs

Refseq ID	NM_000787
Gene ID	1621
Unigene ID	Hs.591890
Probe set ID	206450_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000123454
GTEx ID	ENSG00000123454

Orthologous Gene

Mouse[1]	NM_138942
Rat [0]

Chromosomal Region

9q34.2 [136,501,482 - 136,524,466]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR005018

DOMON related

Gene Ontology (GO ID)

Biological Process

GO:0048149	behavioral response to ethanol
GO:0001974	blood vessel remodeling
GO:0042423	catecholamine biosynthetic process
GO:0034641	cellular nitrogen compound metabolic process
GO:0001816	cytokine production
GO:0042420	dopamine catabolic process
GO:0042596	fear response
GO:0042593	glucose homeostasis
GO:0042309	homoiothermy
GO:0002443	leukocyte mediated immunity
GO:0050900	leukocyte migration
GO:0007626	locomotory behavior
GO:0042711	maternal behavior
GO:0007613	memory
GO:0042421	norepinephrine biosynthetic process
GO:0045907	positive regulation of vasoconstriction
GO:0042981	regulation of apoptosis
GO:0042127	regulation of cell proliferation
GO:0001975	response to amphetamine
GO:0048265	response to pain
GO:0007268	synaptic transmission
GO:0008542	visual learning

Cellular Component

GO:0042583	chromaffin granule
GO:0034466	chromaffin granule lumen
GO:0042584	chromaffin granule membrane
GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0034774	secretory granule lumen
GO:0030658	transport vesicle membrane

Molecular Function

GO:0003824	catalytic activity
GO:0005507	copper ion binding
GO:0004500	dopamine beta-monooxygenase activity
GO:0031418	L-ascorbic acid binding

dopamine beta-hydroxylase (dopamine beta-monooxygenase)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function