DEAD (Asp-Glu-Ala-Asp) box polypeptide 5

Synonym

Probable ATP-dependent RNA helicase DDX5, DDX5, HUMP68, HELR, p68, HLR1, RNA helicase p68, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, DEAD box protein 5, DKFZp686J01190, G17P1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1339.20

cerebellum:2544

brain stem:-

corpus callosum/glia:1545.50

pineal gland:296.70

peripheral nerve:797.50

spine:1235.30

retina:118.60

eye:429

artery/aorta:1948.40

vein:466.50

lymphnode:455

peripheral blood:1111.30

spleen:3006.10

thymus:3478.60

bone marrow:984

adipose:1089

bone:1228.30

skin:777.60

GeneChip

cerebrum:10.10

cerebellum:10.52

brain stem:10.15

corpus callosum/glia:10.61

pineal gland:-

peripheral nerve:10.33

spine:10.59

retina:-

eye:-

artery/aorta:10.60

vein:10.83

lymphnode:11.33

peripheral blood:-

spleen:11.45

thymus:11.84

bone marrow:10.47

adipose:11.11

bone:-

skin:10.91

CAGE

cerebrum:6.75

cerebellum:-

brain stem:6.65

corpus callosum/glia:6.69

pineal gland:7.18

peripheral nerve:-

spine:7.21

retina:-

eye:-

artery/aorta:6.88

vein:6.96

lymphnode:6.92

peripheral blood:-

spleen:6.79

thymus:6.91

bone marrow:-

adipose:6.83

bone:-

skin:-

RNA-seq

cerebrum:6.56

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:7.01

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:6.55

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:3399.20

placenta:484.50

prostate:743.50

ovary:186.30

testis:1289.30

heart:536.40

muscle:261.20

esophagus:342.80

stomach:828.40

intestine:1587.50

colon:339.20

liver/hepato:411.70

lung:2238.50

bladder:2386.60

kidney:488.70

pituitary:2435.60

thyroid/parathyroid:818.70

adrenal gland:2437.80

pancreas:320.10

breast:381

salivary:328.40

GeneChip

uterus:11.17

placenta:10.11

prostate:11.38

ovary:10.80

testis:10.84

heart:10.42

muscle:9.74

esophagus:10.58

stomach:10.87

intestine:10.36

colon:9.87

liver/hepato:10.27

lung:11.37

bladder:-

kidney:10.36

pituitary:11.34

thyroid/parathyroid:11.03

adrenal gland:11.42

pancreas:9.17

breast:10.73

salivary:10.30

CAGE

uterus:6.81

placenta:6.11

prostate:6.41

ovary:6.62

testis:6.34

heart:6.83

muscle:6.35

esophagus:6.39

stomach:-

intestine:6.44

colon:6.46

liver/hepato:6.29

lung:7.00

bladder:6.67

kidney:6.62

pituitary:7.39

thyroid/parathyroid:6.35

adrenal gland:-

pancreas:5.93

breast:7.30

salivary:6.55

RNA-seq

uterus:-

placenta:-

prostate:6.82

ovary:7.30

testis:7.00

heart:6.00

muscle:4.46

esophagus:-

stomach:-

intestine:-

colon:5.75

liver/hepato:5.94

lung:6.78

bladder:-

kidney:6.82

pituitary:-

thyroid/parathyroid:7.36

adrenal gland:7.40

pancreas:-

breast:6.68

salivary:-

IDs

Refseq ID	NM_004396
Gene ID	1655
Unigene ID	Hs.279806
Probe set ID	200033_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000108654
GTEx ID	ENSG00000108654

Orthologous Gene

Mouse[4]	NM_007840
Rat[1]	NM_001007613

Chromosomal Region

17q23.3 [62,494,374 - 62,502,484]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR014001	DEAD-like helicase, N-terminal
IPR014021	Helicase, superfamily 1/2, ATP-binding domain

Gene Ontology (GO ID)

Biological Process

GO:0016049	cell growth
GO:0007623	circadian rhythm
GO:0001701	in utero embryonic development
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000398	nuclear mRNA splicing, via spliceosome
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0033148	positive regulation of estrogen receptor signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome
GO:0060765	regulation of androgen receptor signaling pathway
GO:0045667	regulation of osteoblast differentiation
GO:0045069	regulation of viral genome replication
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0071013	catalytic step 2 spliceosome
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0030529	ribonucleoprotein complex

Molecular Function

GO:0050681	androgen receptor binding
GO:0005524	ATP binding
GO:0004004	ATP-dependent RNA helicase activity
GO:0048306	calcium-dependent protein binding
GO:0005516	calmodulin binding
GO:0019899	enzyme binding
GO:0030331	estrogen receptor binding
GO:0005515	protein binding
GO:0003724	RNA helicase activity
GO:0003713	transcription coactivator activity

DEAD (Asp-Glu-Ala-Asp) box polypeptide 5

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function