dihydropyrimidinase-like 3

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Synonym

Collapsin response mediator protein 4, DPYSL3, DRP3, ULIP protein, Unc-33-like phosphoprotein, CRMP4, dihydropyrimidinase-like 3, CRMP-4, DRP-3, Dihydropyrimidinase-related protein 3, ULIP

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:293.90 cerebellum:12.60 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:276 spine:336.90 retina:711.80 eye:252.70 artery/aorta:119.90 vein:- lymphnode:- peripheral blood:164 spleen:56.70 thymus:12.90 bone marrow:19.70 adipose:161.30 bone:115.20 skin:96
GeneChip cerebrum:4.74 cerebellum:4.56 brain stem:5.19 corpus callosum/glia:4.90 pineal gland:- peripheral nerve:6.26 spine:6.20 retina:- eye:- artery/aorta:5.98 vein:6.52 lymphnode:4.05 peripheral blood:- spleen:4.13 thymus:3.90 bone marrow:3.94 adipose:4.90 bone:- skin:4.33
CAGE cerebrum:3.69 cerebellum:- brain stem:3.90 corpus callosum/glia:4.33 pineal gland:4.28 peripheral nerve:- spine:4.70 retina:- eye:- artery/aorta:5.39 vein:4.10 lymphnode:3.21 peripheral blood:- spleen:3.01 thymus:0.94 bone marrow:- adipose:3.78 bone:- skin:-
RNA-seq cerebrum:4.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.66 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.76 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:236.90 placenta:58.30 prostate:169 ovary:149.10 testis:64.90 heart:357.60 muscle:60.30 esophagus:- stomach:42.50 intestine:- colon:93.30     liver/hepato:-        lung:190.60    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:44.50 breast:111.50 salivary:-
GeneChip uterus:5.77 placenta:4.31 prostate:6 ovary:6.15 testis:4.21 heart:5.14 muscle:4.98 esophagus:5.02 stomach:5.01 intestine:5.47 colon:5.31 liver/hepato:4.04 lung:4.91 bladder:- kidney:4.02 pituitary:4.29 thyroid/parathyroid:4.12 adrenal gland:3.94 pancreas:4.15 breast:4.51 salivary:4.10
CAGE uterus:4.76 placenta:2.14 prostate:4.89 ovary:4.67 testis:3.78 heart:4.20 muscle:3.77 esophagus:4.63 stomach:- intestine:3.29 colon:3.88     liver/hepato:1.33    lung:3.44 bladder:5.06 kidney:1.98 pituitary:2.19 thyroid/parathyroid:3.01 adrenal gland:- pancreas:1.74 breast:3.49 salivary:2.90
RNA-seq uterus:- placenta:- prostate:6.79 ovary:6.26 testis:5.83 heart:3.02 muscle:4.50 esophagus:- stomach:- intestine:- colon:5.76     liver/hepato:0.79        lung:4.80    bladder:- kidney:2.86 pituitary:- thyroid/parathyroid:3.49 adrenal gland:5.22 pancreas:- breast:4.43 salivary:-

Gene Information

IDs

Refseq ID NM_001387
Gene ID 1809
Unigene ID Hs.519659
Probe set ID 201430_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000113657
GTEx ID ENSG00000113657

Orthologous Gene

Mouse[9]  NM_001136086, NM_009468
Rat[1]  NM_012934, NM_009468

Chromosomal Region

5q32  [146,770,374  -  146,889,619]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1602151
8973361
9115293
10664068
10748015
10956643
11771764
12134159
12444086
12477932
12745088
15345747
15933812
16611631
17043677
17081983
18029348
20379614
20543870
20804502
20977846
21044950
21139048
21179545
21319273
22863883
23000965
23568759
24011394
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0051764  actin crosslink formation
GO:0051017  actin filament bundle formation
GO:0007411  axon guidance
GO:0071345  cellular response to cytokine stimulus
GO:0030336  negative regulation of cell migration
GO:0010977  negative regulation of neuron projection development
GO:0051491  positive regulation of filopodium assembly
GO:0010976  positive regulation of neuron projection development
GO:0051260  protein homooligomerization
GO:0006208  pyrimidine base catabolic process
GO:0048678  response to axon injury

Cellular Component

GO:0005829  cytosol
GO:0070382  exocytic vesicle
GO:0005615  extracellular space
GO:0031941  filamentous actin
GO:0030426  growth cone
GO:0030027  lamellipodium

Molecular Function

GO:0016812  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0051219  phosphoprotein binding
GO:0017124  SH3 domain binding