dopamine receptor D1

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Synonym

DRD1, DRD1A, dopamine receptor D1, DADR, D(1A) dopamine receptor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:10.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:148.30

peripheral nerve:-

spine:-

retina:-

eye:17.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:36.40

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4

cerebellum:3.70

brain stem:3.51

corpus callosum/glia:3.65

pineal gland:-

peripheral nerve:3.51

spine:3.49

retina:-

eye:-

artery/aorta:3.42

vein:3.44

lymphnode:3.47

peripheral blood:-

spleen:3.40

thymus:3.37

bone marrow:3.55

adipose:3.41

bone:-

skin:3.36

CAGE

cerebrum:1.25

cerebellum:-

brain stem:0.07

corpus callosum/glia:0.52

pineal gland:0

peripheral nerve:-

spine:0.13

retina:-

eye:-

artery/aorta:0.18

vein:0

lymphnode:0.06

peripheral blood:-

spleen:0

thymus:0.18

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:1.09

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.42

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.09

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:11.30

ovary:-

testis:13

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:21.10

lung:4.90

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.36

placenta:3.48

prostate:3.39

ovary:3.38

testis:3.23

heart:3.53

muscle:3.44

esophagus:3.33

stomach:3.46

intestine:3.48

colon:3.54

liver/hepato:3.56

lung:3.36

bladder:-

kidney:3.52

pituitary:3.40

thyroid/parathyroid:3.38

adrenal gland:3.48

pancreas:3.47

breast:3.42

salivary:3.56

CAGE

uterus:0.13

placenta:0.16

prostate:0.15

ovary:0

testis:0.16

heart:0.09

muscle:0

esophagus:0.09

stomach:-

intestine:0.14

colon:0.04

liver/hepato:0

lung:0.18

bladder:0.40

kidney:0.08

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.65

ovary:0.06

testis:0.19

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.36

liver/hepato:0.04

lung:0.79

bladder:-

kidney:0.19

pituitary:-

thyroid/parathyroid:0.02

adrenal gland:0.32

pancreas:-

breast:0.70

salivary:-

IDs

Refseq ID	NM_000794
Gene ID	1812
Unigene ID	Hs.262480
Probe set ID	214652_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000184845
GTEx ID	ENSG00000184845

Orthologous Gene

Mouse[1]	NM_010076
Rat [0]

Chromosomal Region

5q35.2 [174,867,675 - 174,871,163]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR001413	Dopamine 1A receptor
IPR015694	Dopamine 1A/1B receptor
IPR000929	Dopamine receptor
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007190	activation of adenylate cyclase activity
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway
GO:0007628	adult walking behavior
GO:0014002	astrocyte development
GO:0001662	behavioral fear response
GO:0048148	behavioral response to cocaine
GO:0021853	cerebral cortex GABAergic interneuron migration
GO:0001661	conditioned taste aversion
GO:0021542	dentate gyrus development
GO:0042417	dopamine metabolic process
GO:0015872	dopamine transport
GO:0051482	elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0046323	glucose import
GO:0007625	grooming behavior
GO:0060292	long term synaptic depression
GO:0060291	long-term synaptic potentiation
GO:0007617	mating behavior
GO:0007613	memory
GO:0035106	operant conditioning
GO:0030432	peristalsis
GO:0010579	positive regulation of adenylate cyclase activity by G-protein signaling pathway
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0030335	positive regulation of cell migration
GO:0043268	positive regulation of potassium ion transport
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
GO:0051968	positive regulation of synaptic transmission, glutamatergic
GO:0060134	prepulse inhibition
GO:0006606	protein import into nucleus
GO:0019228	regulation of action potential in neuron
GO:0042053	regulation of dopamine metabolic process
GO:0051584	regulation of dopamine uptake
GO:0001975	response to amphetamine
GO:0042493	response to drug
GO:0046960	sensitization
GO:0021756	striatum development
GO:0007416	synapse assembly
GO:0001963	synaptic transmission, dopaminergic
GO:0001659	temperature homeostasis
GO:0019226	transmission of nerve impulse
GO:0042311	vasodilation
GO:0008542	visual learning

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0005887	integral to plasma membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0035240	dopamine binding
GO:0004952	dopamine receptor activity
GO:0001588	dopamine receptor activity, coupled via Gs
GO:0005515	protein binding

dopamine receptor D1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function