polyhomeotic homolog 1 (Drosophila)

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Synonym

PHC1, HPH1, PH1, polyhomeotic-like 1 (Drosophila), hPH1, Polyhomeotic-like protein 1, EDR1, polyhomeotic homolog 1 (Drosophila), Early development regulatory protein 1, RAE28

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:64 cerebellum:50.40 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:- retina:355.90 eye:94 artery/aorta:119.90 vein:66.60 lymphnode:60.70 peripheral blood:109.30 spleen:56.70 thymus:12.90 bone marrow:- adipose:- bone:12.80 skin:96
GeneChip cerebrum:6.57 cerebellum:7.18 brain stem:6.15 corpus callosum/glia:6.79 pineal gland:- peripheral nerve:6.72 spine:6.82 retina:- eye:- artery/aorta:6.71 vein:6.45 lymphnode:6.77 peripheral blood:- spleen:6.75 thymus:8.18 bone marrow:5.90 adipose:6.64 bone:- skin:6.11
CAGE cerebrum:2.81 cerebellum:- brain stem:2.13 corpus callosum/glia:1.94 pineal gland:3.31 peripheral nerve:- spine:2.17 retina:- eye:- artery/aorta:2.05 vein:1.98 lymphnode:1.14 peripheral blood:- spleen:0.92 thymus:1.44 bone marrow:- adipose:0.78 bone:- skin:-
RNA-seq cerebrum:2.02 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.33 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.44 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:100.20 placenta:105.60 prostate:78.90 ovary:298.10 testis:129.80 heart:102.20 muscle:- esophagus:- stomach:- intestine:64.80 colon:50.90     liver/hepato:31.70        lung:63.50    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:71.10 breast:83.60 salivary:-
GeneChip uterus:7.33 placenta:7.03 prostate:7.08 ovary:7.18 testis:8.12 heart:6.51 muscle:6.14 esophagus:6.62 stomach:6.70 intestine:6.31 colon:6.35 liver/hepato:5.72 lung:6.60 bladder:- kidney:6.68 pituitary:7.96 thyroid/parathyroid:7.23 adrenal gland:6.31 pancreas:5.78 breast:6.70 salivary:6.52
CAGE uterus:2.28 placenta:1.64 prostate:2.04 ovary:1.87 testis:2.28 heart:1.44 muscle:1.41 esophagus:1.66 stomach:- intestine:1.17 colon:1.96     liver/hepato:0.26    lung:1.46 bladder:1.86 kidney:1.14 pituitary:3.43 thyroid/parathyroid:1.19 adrenal gland:- pancreas:0.58 breast:0.90 salivary:2.01
RNA-seq uterus:- placenta:- prostate:3.26 ovary:3.81 testis:4.30 heart:2.23 muscle:2.73 esophagus:- stomach:- intestine:- colon:3.12     liver/hepato:0.60        lung:2.85    bladder:- kidney:2.56 pituitary:- thyroid/parathyroid:2.97 adrenal gland:2.78 pancreas:- breast:2.58 salivary:-

Gene Information

IDs

Refseq ID NM_004426
Gene ID 1911
Unigene ID Hs.305985
Probe set ID 218338_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000111752
GTEx ID ENSG00000111752

Orthologous Gene

Mouse[2]  NM_001042623, NM_007905
Rat[1]  NM_001107886, NM_007905

Chromosomal Region

12p13.31  [9,066,492  -  9,094,063]

Gene Family (Interpro ID)

IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR013761  Sterile alpha motif-type

Link to Pubmed  (Pubmed ID)

9009205
9121482
9199346
10653359
10902910
12167701
12183370
12477932
14973489
15146197
15386022
15489334
15563468
16169070
16189514
18029348
18650381
19322201
19636380
20301772
22321011
22325352
23080069
23207902
23418308
23523425
24097068
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0071300  cellular response to retinoic acid
GO:0007275  multicellular organismal development

Cellular Component

GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0031519  PcG protein complex
GO:0035102  PRC1 complex
GO:0001739  sex chromatin

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0008270  zinc ion binding