ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

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Synonym

Hu-antigen B, HUB, HuB, ELAV-like protein 2, HEL-N1, HELN1, Nervous system-specific RNA-binding protein Hel-N1, abnormal vision, ELAVL2, ELAV-like neuronal protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:37.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.30 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:5.48 cerebellum:5.88 brain stem:6.53 corpus callosum/glia:3.71 pineal gland:- peripheral nerve:6.13 spine:4.60 retina:- eye:- artery/aorta:3.40 vein:3.35 lymphnode:3.40 peripheral blood:- spleen:3.40 thymus:3.40 bone marrow:3.54 adipose:3.47 bone:- skin:3.36
CAGE cerebrum:3.93 cerebellum:- brain stem:3.05 corpus callosum/glia:2.04 pineal gland:0.71 peripheral nerve:- spine:2.78 retina:- eye:- artery/aorta:0.59 vein:0.34 lymphnode:0.32 peripheral blood:- spleen:0.25 thymus:0.06 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:3.68 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.14 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:149.10 testis:103.80 heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:3.34 placenta:3.60 prostate:3.34 ovary:3.28 testis:6.07 heart:3.44 muscle:3.51 esophagus:3.29 stomach:3.41 intestine:3.52 colon:3.49 liver/hepato:3.40 lung:3.22 bladder:- kidney:3.40 pituitary:3.56 thyroid/parathyroid:3.30 adrenal gland:3.35 pancreas:3.62 breast:3.42 salivary:3.38
CAGE uterus:0.71 placenta:0 prostate:0.58 ovary:0.60 testis:3.76 heart:0.34 muscle:0.13 esophagus:0.26 stomach:- intestine:0.14 colon:0.50     liver/hepato:0    lung:0 bladder:0.26 kidney:0 pituitary:2.53 thyroid/parathyroid:0.06 adrenal gland:- pancreas:0 breast:0 salivary:0.62
RNA-seq uterus:- placenta:- prostate:0.15 ovary:0.26 testis:2.36 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0        lung:0    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.07 salivary:-

Gene Information

IDs

Refseq ID NM_004432
Gene ID 1993
Unigene ID Hs.166109
Probe set ID 208427_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000107105
GTEx ID ENSG00000107105

Orthologous Gene

Mouse[9]  NM_001177883, NM_010486, NM_207685, NM_207686
Rat[1]  NM_173309, NM_010486, NM_207685, NM_207686

Chromosomal Region

9p21.3  [23,690,102  -  23,826,335]

Gene Family (Interpro ID)

IPR002343  Paraneoplastic encephalomyelitis antigen
IPR000504  RNA recognition motif, RNP-1
IPR006548  Splicing factor ELAV/HuD

Link to Pubmed  (Pubmed ID)

7828887
7972035
8158249
8812435
8907704
10848602
12384599
12477932
15164053
15489334
15671036
17289661
18607064
19197348
20020773
20211142
20818722
21139048
21145461
21319273
21890473
21963094
22053931
23000965
23512105
24457600
24778252

Gene Ontology  (GO ID)

Biological Process

GO:0006355  regulation of transcription, DNA-dependent

Molecular Function

GO:0003730  mRNA 3'-UTR binding
GO:0000166  nucleotide binding
GO:0005515  protein binding