estrogen-related receptor beta

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Synonym

ERR beta-2, ERRb, ERRB2, ESRL2, ERRbeta, ERR-beta, Estrogen receptor-like 2, Steroid hormone receptor ERR2, ERRbeta-2, ERR2, ESRRB, NR3B2, Estrogen-related receptor, beta, estrogen-related receptor beta

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:355.90 eye:76.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0.25 cerebellum:- brain stem:0.42 corpus callosum/glia:0.63 pineal gland:0.14 peripheral nerve:- spine:0.52 retina:- eye:- artery/aorta:0 vein:0.34 lymphnode:0.41 peripheral blood:- spleen:0.84 thymus:0 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:0.15 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.06 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:7.30 prostate:- ovary:- testis:4.30 heart:- muscle:20.10 esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:21.10        lung:-    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:0.07 placenta:0 prostate:0 ovary:0 testis:0.21 heart:0.64 muscle:1.46 esophagus:0.09 stomach:- intestine:0.07 colon:0     liver/hepato:0.14    lung:0 bladder:0 kidney:2.74 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.01 ovary:0 testis:0.44 heart:1.00 muscle:0.66 esophagus:- stomach:- intestine:- colon:0.03     liver/hepato:0.05        lung:0    bladder:- kidney:2.69 pituitary:- thyroid/parathyroid:0.28 adrenal gland:0.17 pancreas:- breast:0.19 salivary:-

Gene Information

IDs

Refseq ID NM_004452
Gene ID 2103
Unigene ID Hs.435845
Probe set ID -
Ensembl ID ENSG00000119715
GTEx ID ENSG00000119715

Orthologous Gene

Mouse[4]  NM_001159500, NM_011934
Rat [0]  

Chromosomal Region

14q24.3  [76,776,957  -  76,968,178]

Gene Family (Interpro ID)

IPR001723  Steroid hormone receptor
IPR013088  Zinc finger, NHR/GATA-type
IPR001628  Zinc finger, nuclear hormone receptor-type

Link to Pubmed  (Pubmed ID)

3267207
8889548
9344655
9398750
10072763
10598588
12477932
12508121
12529709
12654265
15598686
16332939
16439465
17920186
18071305
18179891
18509053
18775884
18846501
18957414
19196830
19755138
20080650
20301607
20379614
20400511
20634891
21177257
21561608
21802533
22951369
24667650

Gene Ontology  (GO ID)

Biological Process

GO:0001892  embryonic placenta development
GO:0010467  gene expression
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0019827  stem cell maintenance
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0001834  trophectodermal cell proliferation
GO:0001831  trophectodermal cellular morphogenesis

Cellular Component

GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0004879  ligand-dependent nuclear receptor activity
GO:0043565  sequence-specific DNA binding
GO:0005496  steroid binding
GO:0003707  steroid hormone receptor activity
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding
GO:0008270  zinc ion binding