SNW domain containing 1

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Synonym

SKIIP, Nuclear protein SkiP, NCOA-62, SNW1, Prp45, Bx42, Ski-interacting protein, MGC119379, NCoA-62, Nuclear receptor coactivator NCoA-62, PRPF45, SNW domain-containing protein 1, SKI interacting protein, SNW domain containing 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:474.60 eye:35.30 artery/aorta:149.90 vein:66.60 lymphnode:60.70 peripheral blood:18.20 spleen:18.90 thymus:38.70 bone marrow:118.10 adipose:80.70 bone:- skin:24
GeneChip cerebrum:7.22 cerebellum:7.36 brain stem:7.30 corpus callosum/glia:7.50 pineal gland:- peripheral nerve:7.54 spine:7.34 retina:- eye:- artery/aorta:7.78 vein:7.99 lymphnode:7.90 peripheral blood:- spleen:7.85 thymus:7.98 bone marrow:7.83 adipose:7.61 bone:- skin:7.84
CAGE cerebrum:3.43 cerebellum:- brain stem:3.50 corpus callosum/glia:3.62 pineal gland:3.77 peripheral nerve:- spine:3.50 retina:- eye:- artery/aorta:3.15 vein:3.38 lymphnode:3.43 peripheral blood:- spleen:3.73 thymus:3.69 bone marrow:- adipose:3.67 bone:- skin:-
RNA-seq cerebrum:4.52 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.46 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.92 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:32.80 prostate:101.40 ovary:- testis:26 heart:102.20 muscle:522.40 esophagus:- stomach:21.20 intestine:- colon:67.80     liver/hepato:42.20        lung:4.90    bladder:- kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:26.70 breast:74.30 salivary:328.40
GeneChip uterus:7.98 placenta:7.63 prostate:7.76 ovary:8.15 testis:8.58 heart:7.54 muscle:7.57 esophagus:7.70 stomach:7.51 intestine:7.40 colon:7.19 liver/hepato:7.15 lung:7.94 bladder:- kidney:7.23 pituitary:7.50 thyroid/parathyroid:7.73 adrenal gland:7.50 pancreas:6.99 breast:7.95 salivary:7.42
CAGE uterus:3.72 placenta:3.64 prostate:3.69 ovary:3.70 testis:3.93 heart:3.26 muscle:3.91 esophagus:3.62 stomach:- intestine:3.64 colon:3.26     liver/hepato:3.23    lung:3.37 bladder:3.74 kidney:3.36 pituitary:3.68 thyroid/parathyroid:3.67 adrenal gland:- pancreas:2.94 breast:3.54 salivary:3.50
RNA-seq uterus:- placenta:- prostate:4.86 ovary:5.10 testis:5.68 heart:3.63 muscle:4.56 esophagus:- stomach:- intestine:- colon:4.65     liver/hepato:3.40        lung:4.73    bladder:- kidney:4.14 pituitary:- thyroid/parathyroid:5.16 adrenal gland:4.77 pancreas:- breast:4.58 salivary:-

Gene Information

IDs

Refseq ID NM_012245
Gene ID 22938
Unigene ID Hs.445498
Probe set ID 201575_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000100603
GTEx ID ENSG00000100603

Orthologous Gene

Mouse[2]  NM_025507
Rat [0]  

Chromosomal Region

14q24.3  [78,183,942  -  78,227,550]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9569025
9632709
10644367
10713164
11278756
11371506
11404076
11509665
11514567
11522815
11991638
12101239
12466551
12477932
12508107
12508121
12529369
12549820
12650714
12840015
14985122
15194481
15316101
15489334
15546612
15604093
15635413
15878163
15905409
16002321
16083285
16102918
16159877
16169070
16595688
17643375
18029348
18654987
18729074
18854154
18996344
19616115
19818711
19852851
19934264
20007319
20056645
20211142
20227660
20360068
20368803
20467438
20508642
20965173
21139048
21145461
21460037
21461980
21900206
22172677
22178446
22365833
22586326
22872573
22939629
22944692
23000965
23084401
23566155
23696020
23752268
24163370
24250222
24457600
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0071300  cellular response to retinoic acid
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0010467  gene expression
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0007219  Notch signaling pathway
GO:0000398  nuclear mRNA splicing, via spliceosome
GO:0043923  positive regulation by host of viral transcription
GO:0051571  positive regulation of histone H3-K4 methylation
GO:0050769  positive regulation of neurogenesis
GO:0048026  positive regulation of nuclear mRNA splicing, via spliceosome
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0070564  positive regulation of vitamin D receptor signaling pathway
GO:0048385  regulation of retinoic acid receptor signaling pathway
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0070562  regulation of vitamin D receptor signaling pathway
GO:0048384  retinoic acid receptor signaling pathway
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0019048  virus-host interaction

Cellular Component

GO:0071013  catalytic step 2 spliceosome
GO:0000785  chromatin
GO:0016363  nuclear matrix
GO:0044428  nuclear part
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0008024  positive transcription elongation factor complex b
GO:0071146  SMAD3-SMAD4 protein complex
GO:0005681  spliceosomal complex

Molecular Function

GO:0005112  Notch binding
GO:0035257  nuclear hormone receptor binding
GO:0005515  protein binding
GO:0042974  retinoic acid receptor binding
GO:0046332  SMAD binding
GO:0003713  transcription coactivator activity
GO:0003714  transcription corepressor activity
GO:0042809  vitamin D receptor binding