ubiquitin specific peptidase 33

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Synonym

USP33, Ubiquitin carboxyl-terminal hydrolase 33, ubiquitin specific peptidase 33, Ubiquitin thioesterase 33, ubiquitin specific protease 33, KIAA1097, VHL-interacting deubiquitinating enzyme 1, Deubiquitinating enzyme 33, MGC16868, Ubiquitin-specific-processing protease 33, VDU1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8.12 cerebellum:8.71 brain stem:8.18 corpus callosum/glia:7.88 pineal gland:- peripheral nerve:8.20 spine:7.83 retina:- eye:- artery/aorta:7.35 vein:7.10 lymphnode:7.66 peripheral blood:- spleen:7.96 thymus:8.44 bone marrow:7.39 adipose:8.17 bone:- skin:7.61
CAGE cerebrum:4.10 cerebellum:- brain stem:4.14 corpus callosum/glia:3.85 pineal gland:4.43 peripheral nerve:- spine:3.90 retina:- eye:- artery/aorta:3.50 vein:3.75 lymphnode:3.49 peripheral blood:- spleen:3.61 thymus:3.90 bone marrow:- adipose:3.99 bone:- skin:-
RNA-seq cerebrum:0.87 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.42 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.98 placenta:8.28 prostate:8.42 ovary:7.97 testis:7.19 heart:7.10 muscle:6.81 esophagus:7.26 stomach:7.46 intestine:7.24 colon:6.38 liver/hepato:7.18 lung:7.77 bladder:- kidney:7.27 pituitary:7.86 thyroid/parathyroid:7.91 adrenal gland:7.89 pancreas:5.92 breast:7.83 salivary:7.39
CAGE uterus:3.90 placenta:4.23 prostate:3.75 ovary:3.62 testis:3.53 heart:3.58 muscle:3.38 esophagus:3.51 stomach:- intestine:3.90 colon:3.69     liver/hepato:3.15    lung:3.78 bladder:3.64 kidney:3.68 pituitary:3.90 thyroid/parathyroid:3.62 adrenal gland:- pancreas:3.16 breast:4.20 salivary:3.68
RNA-seq uterus:- placenta:- prostate:0.42 ovary:0.21 testis:0.21 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.72        lung:0.37    bladder:- kidney:1.27 pituitary:- thyroid/parathyroid:0.54 adrenal gland:0.73 pancreas:- breast:0.40 salivary:-

Gene Information

IDs

Refseq ID NM_015017
Gene ID 23032
Unigene ID -
Probe set ID 212513_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000077254
GTEx ID ENSG00000077254

Orthologous Gene

Mouse[2]  NM_001076676, NM_133247
Rat [0]  

Chromosomal Region

1p31.1  [78,161,672  -  78,225,537]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
10470851
11739384
12056827
12477932
12838346
12865408
14702039
15489334
15996926
16169070
17452445
17766394
19118533
19322201
19363159
19424180
19615732
19684588
19699092
19706539
19832994
20724312
21139048
21801292
21906983
21963094
22118674
22626734
23000965
23166351
23486064
24056301
24196352

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0016477  cell migration
GO:0051298  centrosome duplication
GO:0006897  endocytosis
GO:0016579  protein deubiquitination
GO:0071108  protein K48-linked deubiquitination
GO:0070536  protein K63-linked deubiquitination
GO:0008277  regulation of G-protein coupled receptor protein signaling pathway
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005794  Golgi apparatus
GO:0048471  perinuclear region of cytoplasm
GO:0030891  VCB complex

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0001664  G-protein-coupled receptor binding
GO:0005515  protein binding
GO:0043130  ubiquitin binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004843  ubiquitin-specific protease activity
GO:0008270  zinc ion binding