KN motif and ankyrin repeat domains 1

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Synonym

MGC43128, Kidney ankyrin repeat-containing protein, ankyrin repeat domain 15, ANKRD15, KANK, Ankyrin repeat domain-containing protein 15, KIAA0172, DKFZp451G231

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:90.10 cerebellum:201.50 brain stem:- corpus callosum/glia:29.20 pineal gland:296.70 peripheral nerve:92 spine:224.60 retina:- eye:58.80 artery/aorta:- vein:199.90 lymphnode:80.90 peripheral blood:36.40 spleen:- thymus:12.90 bone marrow:39.40 adipose:161.30 bone:12.80 skin:134.40
GeneChip cerebrum:7.29 cerebellum:7.13 brain stem:7.38 corpus callosum/glia:8.09 pineal gland:- peripheral nerve:7.31 spine:8.28 retina:- eye:- artery/aorta:8.80 vein:8.22 lymphnode:6.65 peripheral blood:- spleen:5.51 thymus:6.16 bone marrow:4.87 adipose:8.23 bone:- skin:8.04
CAGE cerebrum:3.61 cerebellum:- brain stem:3.58 corpus callosum/glia:4.08 pineal gland:2.69 peripheral nerve:- spine:3.98 retina:- eye:- artery/aorta:5.06 vein:3.17 lymphnode:3.20 peripheral blood:- spleen:2.16 thymus:1.89 bone marrow:- adipose:3.65 bone:- skin:-
RNA-seq cerebrum:0.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:72.90 prostate:169 ovary:74.50 testis:125.50 heart:89.40 muscle:80.40 esophagus:342.80 stomach:21.20 intestine:32.40 colon:212     liver/hepato:10.60        lung:127.10    bladder:- kidney:187.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:83.60 salivary:-
GeneChip uterus:8.27 placenta:7.49 prostate:8.50 ovary:7.40 testis:7.02 heart:8.42 muscle:7.60 esophagus:8.44 stomach:7.13 intestine:7.33 colon:7.25 liver/hepato:8.39 lung:6.70 bladder:- kidney:7.94 pituitary:7.49 thyroid/parathyroid:7.23 adrenal gland:6.53 pancreas:6.78 breast:7.91 salivary:7.10
CAGE uterus:4.08 placenta:3.48 prostate:4.02 ovary:2.80 testis:3.51 heart:3.39 muscle:2.94 esophagus:3.73 stomach:- intestine:2.59 colon:3.08     liver/hepato:3.86    lung:2.89 bladder:4.24 kidney:3.54 pituitary:4.17 thyroid/parathyroid:3.25 adrenal gland:- pancreas:3.29 breast:3.64 salivary:3.42
RNA-seq uterus:- placenta:- prostate:0.84 ovary:0.58 testis:0.37 heart:0.17 muscle:0.23 esophagus:- stomach:- intestine:- colon:0.89     liver/hepato:0.15        lung:0.09    bladder:- kidney:0.43 pituitary:- thyroid/parathyroid:3.60 adrenal gland:0.48 pancreas:- breast:1.87 salivary:-

Gene Information

IDs

Refseq ID NM_153186
Gene ID 23189
Unigene ID Hs.306764
Probe set ID 213005_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000107104
GTEx ID ENSG00000107104

Orthologous Gene

Mouse[1]  NM_181404
Rat[1]  NM_001037197

Chromosomal Region

9p24.3  [470,291  -  746,105]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8724849
12133830
12477932
15164053
15231748
15342556
15489334
15596059
15823577
16344560
16968744
17996375
18029348
18458160
19171758
19506219
19554261
19559006
19834503
20073072
20164854
20360068
20379614
21685469
22084092
22321011
22424883
22876580
22952844
23454270
23793025

Gene Ontology  (GO ID)

Biological Process

GO:0030837  negative regulation of actin filament polymerization
GO:0030336  negative regulation of cell migration
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0010977  negative regulation of neuron projection development
GO:0035024  negative regulation of Rho protein signal transduction
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0032587  ruffle membrane

Molecular Function

GO:0008013  beta-catenin binding
GO:0005515  protein binding