flavin containing monooxygenase 2 (non-functional)

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Synonym

FMO 2, FMO2, flavin containing monooxygenase 2, FMO1B1, Pulmonary flavin-containing monooxygenase 2, FMO 1B1, Dimethylaniline oxidase 2, FLJ40826, Dimethylaniline monooxygenase [N-oxide-forming] 2, flavin containing monooxygenase 2 (non-functional)

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:112.30 retina:- eye:41.10 artery/aorta:60 vein:- lymphnode:- peripheral blood:- spleen:- thymus:25.80 bone marrow:- adipose:201.70 bone:25.60 skin:57.60
GeneChip cerebrum:5 cerebellum:4.66 brain stem:5.24 corpus callosum/glia:4.96 pineal gland:- peripheral nerve:7.91 spine:5.65 retina:- eye:- artery/aorta:8.88 vein:7.82 lymphnode:7.84 peripheral blood:- spleen:4.71 thymus:6.83 bone marrow:6.98 adipose:8.64 bone:- skin:7.47
CAGE cerebrum:0.87 cerebellum:- brain stem:1.25 corpus callosum/glia:0.79 pineal gland:1.27 peripheral nerve:- spine:1.52 retina:- eye:- artery/aorta:3.97 vein:3.19 lymphnode:2.15 peripheral blood:- spleen:0.17 thymus:0.57 bone marrow:- adipose:4.18 bone:- skin:-
RNA-seq cerebrum:0.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.88 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.79 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:- prostate:45.10 ovary:- testis:21.60 heart:25.50 muscle:20.10 esophagus:685.60 stomach:- intestine:97.20 colon:8.50     liver/hepato:21.10        lung:215.10    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:- breast:9.30 salivary:-
GeneChip uterus:5.88 placenta:4.82 prostate:5.68 ovary:6.68 testis:4.57 heart:9.42 muscle:7.02 esophagus:8.15 stomach:6.44 intestine:5.95 colon:5.75 liver/hepato:5.91 lung:11.22 bladder:- kidney:6.56 pituitary:6 thyroid/parathyroid:6.56 adrenal gland:9.21 pancreas:6.13 breast:8.47 salivary:7.63
CAGE uterus:2.04 placenta:0 prostate:2.44 ovary:2.40 testis:1.20 heart:3.46 muscle:2.42 esophagus:3.99 stomach:- intestine:1.10 colon:1.46     liver/hepato:1.29    lung:4.72 bladder:2.21 kidney:2.75 pituitary:1.86 thyroid/parathyroid:2.27 adrenal gland:- pancreas:1.21 breast:3.64 salivary:1.28
RNA-seq uterus:- placenta:- prostate:3.30 ovary:1.02 testis:1.91 heart:4.81 muscle:2.37 esophagus:- stomach:- intestine:- colon:4.14     liver/hepato:1.00        lung:6.23    bladder:- kidney:2.68 pituitary:- thyroid/parathyroid:2.53 adrenal gland:3.34 pancreas:- breast:4.43 salivary:-

Gene Information

IDs

Refseq ID NM_001460
Gene ID 2327
Unigene ID Hs.144912
Probe set ID 211726_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000094963
GTEx ID ENSG00000094963

Orthologous Gene

Mouse[2]  NM_018881
Rat[1]  NM_144737

Chromosomal Region

1q24.3  [171,154,347  -  171,181,822]

Gene Family (Interpro ID)

IPR012143  Dimethylaniline monooxygenase, N-oxide-forming
IPR002253  Flavin-containing monooxygenase (FMO) 1
IPR002254  Flavin-containing monooxygenase (FMO) 2
IPR002257  Flavin-containing monooxygenase (FMO) 5
IPR000960  Flavin-containing monooxygenase FMO
IPR020946  Flavin-containing monooxygenase-like

Link to Pubmed  (Pubmed ID)

1417778
1542660
7720101
8128486
8311461
8786146
8889548
9804831
11042094
11744609
12477932
12527699
14702039
15144220
15355885
15489334
15864117
16344560
16710414
18794725
19420133
19898482
20173083
20529763

Gene Ontology  (GO ID)

Biological Process

GO:0017144  drug metabolic process
GO:0006739  NADP metabolic process
GO:0070995  NADPH oxidation
GO:0006082  organic acid metabolic process
GO:0009404  toxin metabolic process
GO:0006805  xenobiotic metabolic process

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0016020  membrane

Molecular Function

GO:0050660  FAD binding
GO:0004499  flavin-containing monooxygenase activity
GO:0004497  monooxygenase activity
GO:0050661  NADP or NADPH binding