chromobox homolog 5 (HP1 alpha homolog, Drosophila)

Synonym

Heterochromatin protein 1 homolog alpha, chromobox homolog 5 (Drosophila HP1 alpha), HP1A, HP1-ALPHA, HP1, CBX5, HP1Hs-alpha, HP1 alpha, Antigen p25, Chromobox protein homolog 5

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:135.10

cerebellum:63

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:184

spine:112.30

retina:-

eye:188.10

artery/aorta:-

vein:66.60

lymphnode:121.30

peripheral blood:36.40

spleen:56.70

thymus:154.60

bone marrow:19.70

adipose:-

bone:76.80

skin:67.20

GeneChip

cerebrum:8.03

cerebellum:8.47

brain stem:7.83

corpus callosum/glia:8.22

pineal gland:-

peripheral nerve:7.53

spine:8.32

retina:-

eye:-

artery/aorta:7.16

vein:6.89

lymphnode:7.65

peripheral blood:-

spleen:7.53

thymus:8.37

bone marrow:7.43

adipose:7.07

bone:-

skin:7.28

CAGE

cerebrum:4.69

cerebellum:-

brain stem:4.58

corpus callosum/glia:4.91

pineal gland:4.57

peripheral nerve:-

spine:4.96

retina:-

eye:-

artery/aorta:4.06

vein:4.02

lymphnode:4.15

peripheral blood:-

spleen:4.03

thymus:5.05

bone marrow:-

adipose:4.01

bone:-

skin:-

RNA-seq

cerebrum:0.35

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:45.60

placenta:29.10

prostate:67.60

ovary:37.30

testis:108.20

heart:127.70

muscle:60.30

esophagus:-

stomach:63.70

intestine:32.40

colon:67.80

liver/hepato:63.30

lung:63.50

bladder:-

kidney:93.60

pituitary:-

thyroid/parathyroid:327.50

adrenal gland:-

pancreas:186.70

breast:139.40

salivary:-

GeneChip

uterus:7.52

placenta:6.96

prostate:7.60

ovary:8.08

testis:7.69

heart:6.74

muscle:6.14

esophagus:7.13

stomach:7.18

intestine:6.87

colon:7.23

liver/hepato:6.55

lung:7.16

bladder:-

kidney:7.60

pituitary:8.40

thyroid/parathyroid:8.20

adrenal gland:7.15

pancreas:6.60

breast:7.88

salivary:6.85

CAGE

uterus:4.22

placenta:3.95

prostate:4.11

ovary:4.68

testis:4.47

heart:4.25

muscle:3.87

esophagus:3.92

stomach:-

intestine:3.54

colon:3.70

liver/hepato:3.71

lung:3.77

bladder:3.86

kidney:4.23

pituitary:4.82

thyroid/parathyroid:4.26

adrenal gland:-

pancreas:3.71

breast:3.58

salivary:4.16

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.24

testis:0.07

heart:0.18

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.09

liver/hepato:0.00

lung:0.00

bladder:-

kidney:0.28

pituitary:-

thyroid/parathyroid:0.79

adrenal gland:0.00

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_001127322
Gene ID	23468
Unigene ID	Hs.349283
Probe set ID	212126_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000094916
GTEx ID	ENSG00000094916

Orthologous Gene

Mouse[12]	NM_001076789, NM_001110216, NM_007626
Rat[1]	NM_001106797, NM_001110216, NM_007626

Chromosomal Region

12q13.13 [54,624,724 - 54,673,955]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000953	Chromo domain
IPR017984	Chromo domain subgroup
IPR016197	Chromo domain-like
IPR008251	Chromo shadow
IPR018125	Chromo shadow, subgroup

Gene Ontology (GO ID)

Biological Process

GO:0007596	blood coagulation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0019048	virus-host interaction

Cellular Component

GO:0010369	chromocenter
GO:0005737	cytoplasm
GO:0000118	histone deacetylase complex
GO:0035097	histone methyltransferase complex
GO:0000776	kinetochore
GO:0031618	nuclear centromeric heterochromatin
GO:0005635	nuclear envelope
GO:0005720	nuclear heterochromatin
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0016605	PML body
GO:0017053	transcriptional repressor complex

Molecular Function

GO:0003682	chromatin binding
GO:0019899	enzyme binding
GO:0042826	histone deacetylase binding
GO:0035064	methylated histone residue binding
GO:0005515	protein binding
GO:0030674	protein binding, bridging
GO:0042803	protein homodimerization activity
GO:0070491	transcription repressor binding

chromobox homolog 5 (HP1 alpha homolog, Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function