nuclear receptor subfamily 5, group A, member 2

Synonym

Alpha-1-fetoprotein transcription factor, FTF, B1-binding factor, B1F2, FTZ-F1beta, CYP7A promoter-binding factor, NR5A2, hB1F, nuclear receptor subfamily 5, group A, member 2, Hepatocytic transcription factor, hB1F-2, B1F, LRH-1, FTZ-F1, Orphan nuclear receptor NR5A2, Liver receptor homolog 1, CPF

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:3.59

cerebellum:3.82

brain stem:3.63

corpus callosum/glia:3.71

pineal gland:-

peripheral nerve:3.66

spine:3.69

retina:-

eye:-

artery/aorta:3.70

vein:3.51

lymphnode:3.65

peripheral blood:-

spleen:3.61

thymus:3.77

bone marrow:3.69

adipose:3.66

bone:-

skin:3.68

CAGE

cerebrum:0.09

cerebellum:-

brain stem:0.27

corpus callosum/glia:0.13

pineal gland:0.79

peripheral nerve:-

spine:0.61

retina:-

eye:-

artery/aorta:0.18

vein:1.39

lymphnode:1.13

peripheral blood:-

spleen:0.09

thymus:0.06

bone marrow:-

adipose:1.95

bone:-

skin:-

RNA-seq

cerebrum:0.07

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.81

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.99

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:34.60

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.73

placenta:3.43

prostate:3.47

ovary:3.68

testis:3.34

heart:3.65

muscle:3.62

esophagus:3.53

stomach:3.53

intestine:4.36

colon:3.69

liver/hepato:4.12

lung:3.63

bladder:-

kidney:3.57

pituitary:3.70

thyroid/parathyroid:3.57

adrenal gland:3.58

pancreas:6.02

breast:3.59

salivary:3.37

CAGE

uterus:2.23

placenta:0.08

prostate:1.38

ovary:1.23

testis:0.94

heart:1.12

muscle:0.70

esophagus:1.23

stomach:-

intestine:4.34

colon:3.54

liver/hepato:4.09

lung:1.28

bladder:1.47

kidney:0.67

pituitary:0.26

thyroid/parathyroid:0.79

adrenal gland:-

pancreas:5.17

breast:2.11

salivary:0.36

RNA-seq

uterus:-

placenta:-

prostate:0.45

ovary:1.17

testis:1.37

heart:0.76

muscle:0.50

esophagus:-

stomach:-

intestine:-

colon:0.85

liver/hepato:3.38

lung:1.82

bladder:-

kidney:0.70

pituitary:-

thyroid/parathyroid:0.30

adrenal gland:2.45

pancreas:-

breast:1.77

salivary:-

IDs

Refseq ID	NM_003822
Gene ID	2494
Unigene ID	Hs.334462
Probe set ID	208337_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000116833
GTEx ID	ENSG00000116833

Orthologous Gene

Mouse[6]	NM_001159769, NM_030676
Rat [0]

Chromosomal Region

1q32.1 [199,996,730 - 200,146,552]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016355	Orphan nuclear receptor Fushi-tarazu factor 1
IPR001723	Steroid hormone receptor
IPR013088	Zinc finger, NHR/GATA-type
IPR001628	Zinc finger, nuclear hormone receptor-type

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0008206	bile acid metabolic process
GO:0042632	cholesterol homeostasis
GO:0009790	embryonic development
GO:0031018	endocrine pancreas development
GO:0010467	gene expression
GO:0042592	homeostatic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0045070	positive regulation of viral genome replication
GO:0042127	regulation of cell proliferation
GO:0006355	regulation of transcription, DNA-dependent
GO:0006367	transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005737	cytoplasm
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0003690	double-stranded DNA binding
GO:0004879	ligand-dependent nuclear receptor activity
GO:0005543	phospholipid binding
GO:0005515	protein binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0003707	steroid hormone receptor activity
GO:0003700	transcription factor activity
GO:0008270	zinc ion binding

nuclear receptor subfamily 5, group A, member 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function