guanylate binding protein 2, interferon-inducible

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Synonym

Interferon-induced guanylate-binding protein 2, GBP-2, guanylate binding protein 2, interferon-inducible, Guanine nucleotide-binding protein 2, HuGBP-2, GTP-binding protein 2, GBP2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:34.40 cerebellum:12.60 brain stem:- corpus callosum/glia:145.80 pineal gland:- peripheral nerve:92 spine:- retina:- eye:11.80 artery/aorta:149.90 vein:- lymphnode:202.20 peripheral blood:309.70 spleen:567.20 thymus:283.40 bone marrow:19.70 adipose:80.70 bone:307.10 skin:9.60
GeneChip cerebrum:5.16 cerebellum:5.22 brain stem:5.33 corpus callosum/glia:5.40 pineal gland:- peripheral nerve:6.98 spine:5.64 retina:- eye:- artery/aorta:8.25 vein:8.34 lymphnode:7.86 peripheral blood:- spleen:8.36 thymus:6.73 bone marrow:6.06 adipose:7.76 bone:- skin:7.91
CAGE cerebrum:1.93 cerebellum:- brain stem:2.84 corpus callosum/glia:2.12 pineal gland:3.21 peripheral nerve:- spine:3.68 retina:- eye:- artery/aorta:4.35 vein:3.79 lymphnode:3.66 peripheral blood:- spleen:4.11 thymus:2.71 bone marrow:- adipose:4.55 bone:- skin:-
RNA-seq cerebrum:2.22 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.17 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.69 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:373.60 placenta:61.90 prostate:180.20 ovary:111.80 testis:17.30 heart:51.10 muscle:20.10 esophagus:1028.50 stomach:361.10 intestine:583.20 colon:76.30     liver/hepato:-        lung:151.50    bladder:628.10 kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:507.90 pancreas:26.70 breast:139.40 salivary:-
GeneChip uterus:8.05 placenta:6.82 prostate:7.69 ovary:7.89 testis:5.95 heart:6.86 muscle:6.41 esophagus:7.39 stomach:7.69 intestine:7.02 colon:7.20 liver/hepato:6.77 lung:7.93 bladder:- kidney:5.67 pituitary:5.45 thyroid/parathyroid:6.23 adrenal gland:8.19 pancreas:5.77 breast:7.99 salivary:5.96
CAGE uterus:4.44 placenta:3.60 prostate:4.78 ovary:4.38 testis:3.09 heart:3.41 muscle:3.63 esophagus:4.49 stomach:- intestine:4.47 colon:4.00     liver/hepato:3.54    lung:4.23 bladder:4.96 kidney:3.86 pituitary:2.32 thyroid/parathyroid:3.87 adrenal gland:- pancreas:2.34 breast:4.32 salivary:2.88
RNA-seq uterus:- placenta:- prostate:6.63 ovary:5.66 testis:4.46 heart:2.56 muscle:5.29 esophagus:- stomach:- intestine:- colon:6.29     liver/hepato:3.94        lung:7.11    bladder:- kidney:4.17 pituitary:- thyroid/parathyroid:3.78 adrenal gland:4.75 pancreas:- breast:5.21 salivary:-

Gene Information

IDs

Refseq ID NM_004120
Gene ID 2634
Unigene ID Hs.386567
Probe set ID 202748_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000162645
GTEx ID ENSG00000162645

Orthologous Gene

Mouse[3]  NM_010259, NM_010260
Rat[3]  NM_010259, NM_010260

Chromosomal Region

1p22.2  [89,571,815  -  89,616,139]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1715024
8125298
8706832
8723115
11096456
12107410
12447867
12477932
14702039
16169070
16344560
17517895
18985028
19003964
19912588
20237496
20923658
21151871
21900206
22863883
22864358
22970192
23086406

Gene Ontology  (GO ID)

Biological Process

GO:0019221  cytokine-mediated signaling pathway
GO:0006955  immune response
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0060337  type I interferon-mediated signaling pathway

Cellular Component

GO:0005829  cytosol
GO:0000139  Golgi membrane
GO:0005634  nucleus

Molecular Function

GO:0005525  GTP binding
GO:0003924  GTPase activity