growth differentiation factor 1

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Synonym

GDF-1, GDF1, growth differentiation factor 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:60.40 cerebellum:37.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:112.30 retina:237.30 eye:17.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.36 cerebellum:7.54 brain stem:8.25 corpus callosum/glia:9.47 pineal gland:- peripheral nerve:6.42 spine:9.91 retina:- eye:- artery/aorta:5.15 vein:4.69 lymphnode:4.72 peripheral blood:- spleen:4.56 thymus:4.22 bone marrow:4.74 adipose:4.75 bone:- skin:5.28
CAGE cerebrum:1.82 cerebellum:- brain stem:1.53 corpus callosum/glia:1.64 pineal gland:0.71 peripheral nerve:- spine:2.44 retina:- eye:- artery/aorta:0.18 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:2.67 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.30 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.04 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:7.30 prostate:- ovary:37.30 testis:8.70 heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:10.60        lung:9.80    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:53.30 breast:9.30 salivary:-
GeneChip uterus:4.75 placenta:4.59 prostate:4.43 ovary:4.90 testis:6.57 heart:5.07 muscle:5.89 esophagus:5.66 stomach:4.74 intestine:5.29 colon:5 liver/hepato:4.78 lung:4.78 bladder:- kidney:4.35 pituitary:5.41 thyroid/parathyroid:4.51 adrenal gland:4.30 pancreas:4.93 breast:4.79 salivary:4.98
CAGE uterus:0.07 placenta:0 prostate:0.08 ovary:0 testis:0.92 heart:0.09 muscle:0.51 esophagus:0 stomach:- intestine:0.07 colon:0.04     liver/hepato:0    lung:0.17 bladder:0 kidney:0 pituitary:0.67 thyroid/parathyroid:0.06 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.26 ovary:0.13 testis:0.84 heart:0.06 muscle:0.76 esophagus:- stomach:- intestine:- colon:0.17     liver/hepato:0        lung:0.08    bladder:- kidney:0.04 pituitary:- thyroid/parathyroid:0.12 adrenal gland:0.04 pancreas:- breast:0.13 salivary:-

Gene Information

IDs

Refseq ID NM_001492
Gene ID 2657
Unigene ID Hs.412355
Probe set ID 206397_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130283
ENSG00000223802
GTEx ID ENSG00000130283
ENSG00000223802

Orthologous Gene

Mouse[3]  NM_001163282, NM_008107, NM_138647
Rat[1]  NM_001044230, NM_001044240, NM_138647

Chromosomal Region

19p13.11  [18,979,361  -  19,006,953]

Gene Family (Interpro ID)

IPR002405  Inhibin, alpha subunit
IPR015615  Transforming growth factor-beta-related

Link to Pubmed  (Pubmed ID)

1704486
2034669
8401586
9872981
10844590
12477932
15057824
17924340
19359031
19553149
20413652
20634891
20734064
20807224
23076529
24275554

Gene Ontology  (GO ID)

Biological Process

GO:0040007  growth

Cellular Component

GO:0005615  extracellular space

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity