acyl-Coenzyme A dehydrogenase family, member 8

 jump to detail

Synonym

Activator-recruited cofactor 42 kDa component, acyl-Coenzyme A dehydrogenase family, member 8, Isobutyryl-CoA dehydrogenase, ACAD8, ACAD-8, ARC42, FLJ22590

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:164.70 cerebellum:327.40 brain stem:- corpus callosum/glia:320.80 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:23.50 artery/aorta:30 vein:66.60 lymphnode:40.40 peripheral blood:36.40 spleen:94.50 thymus:219 bone marrow:- adipose:40.30 bone:25.60 skin:86.40
GeneChip cerebrum:5.90 cerebellum:6.18 brain stem:5.76 corpus callosum/glia:6.09 pineal gland:- peripheral nerve:5.88 spine:5.99 retina:- eye:- artery/aorta:5.62 vein:5.14 lymphnode:6.08 peripheral blood:- spleen:6.23 thymus:6.65 bone marrow:6.21 adipose:6.43 bone:- skin:6.31
CAGE cerebrum:3.24 cerebellum:- brain stem:3.21 corpus callosum/glia:3.10 pineal gland:2.87 peripheral nerve:- spine:3.03 retina:- eye:- artery/aorta:2.89 vein:2.79 lymphnode:2.65 peripheral blood:- spleen:2.31 thymus:2.64 bone marrow:- adipose:2.63 bone:- skin:-
RNA-seq cerebrum:2.87 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.89 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.80 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:100.20 placenta:18.20 prostate:123.90 ovary:- testis:30.30 heart:76.60 muscle:- esophagus:- stomach:42.50 intestine:162 colon:59.40     liver/hepato:21.10        lung:78.20    bladder:125.60 kidney:114.40 pituitary:- thyroid/parathyroid:- adrenal gland:203.10 pancreas:35.60 breast:37.20 salivary:-
GeneChip uterus:6.06 placenta:5.28 prostate:7.40 ovary:6.11 testis:5.81 heart:6.40 muscle:6.93 esophagus:6.15 stomach:6.28 intestine:6.20 colon:6.08 liver/hepato:6.87 lung:5.97 bladder:- kidney:7.40 pituitary:5.96 thyroid/parathyroid:7.23 adrenal gland:6.14 pancreas:6.08 breast:6.55 salivary:6.51
CAGE uterus:2.68 placenta:2.08 prostate:2.72 ovary:2.18 testis:2.78 heart:3.09 muscle:3.18 esophagus:2.55 stomach:- intestine:2.52 colon:3.04     liver/hepato:3.03    lung:2.91 bladder:2.54 kidney:3.04 pituitary:2.94 thyroid/parathyroid:3.12 adrenal gland:- pancreas:3.02 breast:3.06 salivary:3.17
RNA-seq uterus:- placenta:- prostate:3.21 ovary:2.85 testis:2.92 heart:3.23 muscle:2.35 esophagus:- stomach:- intestine:- colon:1.98     liver/hepato:3.51        lung:2.10    bladder:- kidney:3.95 pituitary:- thyroid/parathyroid:5.00 adrenal gland:2.68 pancreas:- breast:2.88 salivary:-

Gene Information

IDs

Refseq ID NM_014384
Gene ID 27034
Unigene ID Hs.14791
Probe set ID 221669_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000151498
GTEx ID ENSG00000151498

Orthologous Gene

Mouse[2]  NM_025862
Rat[2]  NM_025862

Chromosomal Region

11q25  [134,123,389  -  134,135,749]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10235267
10524212
11013134
12359132
12477932
14702039
14752098
15489334
16806233
17387528
20360068
20877624
23080069
23251661

Gene Ontology  (GO ID)

Biological Process

GO:0009083  branched chain family amino acid catabolic process
GO:0034641  cellular nitrogen compound metabolic process
GO:0006629  lipid metabolic process
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent
GO:0006574  valine catabolic process

Cellular Component

GO:0005759  mitochondrial matrix

Molecular Function

GO:0003995  acyl-CoA dehydrogenase activity
GO:0050660  FAD binding