LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)

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Synonym

LSM1, CASM, Small nuclear ribonuclear CaSm, Cancer-associated Sm-like, YJL124C, U6 snRNA-associated Sm-like protein LSm1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.70 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:61.30 spine:- retina:- eye:41.10 artery/aorta:60 vein:- lymphnode:60.70 peripheral blood:- spleen:37.80 thymus:- bone marrow:- adipose:- bone:- skin:14.40
GeneChip cerebrum:7.95 cerebellum:7.87 brain stem:8.12 corpus callosum/glia:7.75 pineal gland:- peripheral nerve:7.69 spine:7.90 retina:- eye:- artery/aorta:8.26 vein:8.51 lymphnode:8.13 peripheral blood:- spleen:8 thymus:8.28 bone marrow:7.92 adipose:8.29 bone:- skin:8.24
CAGE cerebrum:3.33 cerebellum:- brain stem:3.25 corpus callosum/glia:3.06 pineal gland:3.48 peripheral nerve:- spine:3.26 retina:- eye:- artery/aorta:3.68 vein:3.23 lymphnode:3.31 peripheral blood:- spleen:3.28 thymus:3.06 bone marrow:- adipose:3.05 bone:- skin:-
RNA-seq cerebrum:2.11 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.49 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.75 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:54.60 prostate:67.60 ovary:- testis:21.60 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:68.40    bladder:- kidney:114.40 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:97.80 breast:- salivary:-
GeneChip uterus:8.38 placenta:8.40 prostate:8.35 ovary:8.38 testis:8.27 heart:8.56 muscle:8.19 esophagus:8.20 stomach:8.21 intestine:8.19 colon:8.08 liver/hepato:8.04 lung:7.99 bladder:- kidney:8.50 pituitary:8.07 thyroid/parathyroid:8.13 adrenal gland:8.40 pancreas:8.14 breast:8.15 salivary:8.48
CAGE uterus:3.28 placenta:3.60 prostate:3.27 ovary:3.20 testis:3.23 heart:3.84 muscle:3.38 esophagus:3.49 stomach:- intestine:3.51 colon:3.41     liver/hepato:3.51    lung:3.10 bladder:3.43 kidney:3.78 pituitary:3.57 thyroid/parathyroid:3.43 adrenal gland:- pancreas:3.50 breast:3.90 salivary:3.56
RNA-seq uterus:- placenta:- prostate:3.55 ovary:3.10 testis:3.71 heart:3.49 muscle:2.22 esophagus:- stomach:- intestine:- colon:3.11     liver/hepato:2.28        lung:2.64    bladder:- kidney:1.85 pituitary:- thyroid/parathyroid:2.98 adrenal gland:3.37 pancreas:- breast:3.20 salivary:-

Gene Information

IDs

Refseq ID NM_014462
Gene ID 27257
Unigene ID Hs.425311
Probe set ID 203534_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000175324
GTEx ID ENSG00000175324

Orthologous Gene

Mouse[1]  NM_026032
Rat[1]  NM_001108876

Chromosomal Region

8p11.23  [38,020,839  -  38,034,248]

Gene Family (Interpro ID)

IPR001163  Like-Sm ribonucleoprotein (LSM) domain
IPR006649  Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type

Link to Pubmed  (Pubmed ID)

8980254
9230209
10369684
10523320
10851237
11920408
11953827
12477932
12515382
14667819
15231747
15342556
15489334
16147992
16699599
16756390
17001308
17178857
18172165
18218995
18559850
20379614
21139048
21788678
22037555
22863883
22939629
24035562
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0043928  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0010467  gene expression
GO:0071044  histone mRNA catabolic process
GO:0016071  mRNA metabolic process
GO:0006397  mRNA processing
GO:0000288  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0016070  RNA metabolic process
GO:0008380  RNA splicing
GO:0000375  RNA splicing, via transesterification reactions

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus
GO:0030529  ribonucleoprotein complex

Molecular Function

GO:0005515  protein binding
GO:0003723  RNA binding