guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

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Synonym

H_LUCA15.1, H_LUCA16.1, GNAI2B, Adenylate cyclase-inhibiting G alpha protein, GNAI2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:195.60

cerebellum:125.90

brain stem:-

corpus callosum/glia:262.50

pineal gland:-

peripheral nerve:276

spine:336.90

retina:118.60

eye:329.10

artery/aorta:689.40

vein:133.30

lymphnode:293.20

peripheral blood:419

spleen:302.50

thymus:141.70

bone marrow:1436.70

adipose:282.30

bone:422.20

skin:254.40

GeneChip

cerebrum:8.16

cerebellum:7.01

brain stem:8.30

corpus callosum/glia:8.83

pineal gland:-

peripheral nerve:8.69

spine:8.92

retina:-

eye:-

artery/aorta:8.93

vein:8.44

lymphnode:8.90

peripheral blood:-

spleen:9.36

thymus:8.21

bone marrow:8.96

adipose:8.87

bone:-

skin:7.94

CAGE

cerebrum:5.27

cerebellum:-

brain stem:5.54

corpus callosum/glia:6.01

pineal gland:4.77

peripheral nerve:-

spine:5.91

retina:-

eye:-

artery/aorta:5.85

vein:6.10

lymphnode:5.91

peripheral blood:-

spleen:6.33

thymus:5.85

bone marrow:-

adipose:6.23

bone:-

skin:-

RNA-seq

cerebrum:5.79

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:6.91

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:7.85

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:227.80

placenta:367.90

prostate:169

ovary:111.80

testis:186

heart:166

muscle:60.30

esophagus:-

stomach:106.20

intestine:32.40

colon:169.60

liver/hepato:84.40

lung:210.20

bladder:251.20

kidney:166.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:71.10

breast:557.60

salivary:-

GeneChip

uterus:8.22

placenta:7.92

prostate:8.03

ovary:8.28

testis:8.16

heart:8.41

muscle:7.18

esophagus:8.21

stomach:8.27

intestine:7.68

colon:7.82

liver/hepato:8.44

lung:9.04

bladder:-

kidney:7.95

pituitary:8.63

thyroid/parathyroid:8.35

adrenal gland:8.42

pancreas:7.22

breast:7.99

salivary:7.39

CAGE

uterus:5.74

placenta:5.90

prostate:5.63

ovary:5.78

testis:5.36

heart:5.84

muscle:5.21

esophagus:5.57

stomach:-

intestine:5.06

colon:5.25

liver/hepato:5.54

lung:6.15

bladder:5.81

kidney:5.18

pituitary:5.24

thyroid/parathyroid:5.26

adrenal gland:-

pancreas:4.15

breast:5.66

salivary:4.45

RNA-seq

uterus:-

placenta:-

prostate:6.84

ovary:6.67

testis:6.17

heart:5.22

muscle:5.05

esophagus:-

stomach:-

intestine:-

colon:6.71

liver/hepato:5.26

lung:7.91

bladder:-

kidney:5.70

pituitary:-

thyroid/parathyroid:5.97

adrenal gland:7.24

pancreas:-

breast:6.72

salivary:-

IDs

Refseq ID	NM_002070
Gene ID	2771
Unigene ID	Hs.77269
Probe set ID	201040_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000114353
GTEx ID	ENSG00000114353

Orthologous Gene

Mouse[2]	NM_008138
Rat [0]

Chromosomal Region

3p21.31 [50,263,724 - 50,296,787]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002975	Fungal G-protein, alpha subunit
IPR001408	G-protein alpha subunit, group I
IPR001019	Guanine nucleotide binding protein (G-protein), alpha subunit

Gene Ontology (GO ID)

Biological Process

GO:0000186	activation of MAPKK activity
GO:0001973	adenosine receptor signaling pathway
GO:0007596	blood coagulation
GO:0007049	cell cycle
GO:0051301	cell division
GO:0008283	cell proliferation
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007214	gamma-aminobutyric acid signaling pathway
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0007213	muscarinic acetylcholine receptor signaling pathway
GO:0007194	negative regulation of adenylate cyclase activity
GO:0050805	negative regulation of synaptic transmission
GO:0030168	platelet activation
GO:0008284	positive regulation of cell proliferation
GO:0007243	protein kinase cascade
GO:0051924	regulation of calcium ion transport
GO:0007584	response to nutrient
GO:0007165	signal transduction
GO:0007268	synaptic transmission

Cellular Component

GO:0005813	centrosome
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0031234	extrinsic to internal side of plasma membrane
GO:0005834	heterotrimeric G-protein complex
GO:0045121	membrane raft
GO:0030496	midbody
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0031683	G-protein beta/gamma-subunit binding
GO:0001664	G-protein-coupled receptor binding
GO:0005525	GTP binding
GO:0003924	GTPase activity
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0004871	signal transducer activity

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function