H6 family homeobox 2

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Synonym

HMX2, Nkx5-2, homeobox (H6 family) 2, homeo box (H6 family) 2, H6L

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.03 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:83.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0.07 heart:0.09 muscle:0 esophagus:0 stomach:- intestine:0.07 colon:0.08     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.08 ovary:0 testis:0.05 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.04     liver/hepato:0        lung:0.01    bladder:- kidney:1.18 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_005519
Gene ID 3167
Unigene ID Hs.444756
Probe set ID -
Ensembl ID ENSG00000188816
GTEx ID ENSG00000188816

Orthologous Gene

Mouse[1]  NM_145998
Rat[1]  NM_001106303

Chromosomal Region

10q26.13  [124,907,638  -  124,910,188]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

7510254
7647458
9004130
12477932
15558495
19253379
20072845

Gene Ontology  (GO ID)

Biological Process

GO:0007420  brain development
GO:0030154  cell differentiation
GO:0042472  inner ear morphogenesis
GO:0008284  positive regulation of cell proliferation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity