acyl-Coenzyme A dehydrogenase, long chain

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Synonym

acyl-Coenzyme A dehydrogenase, long chain, ACADL, LCAD, ACAD4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:12.90 bone marrow:- adipose:- bone:25.60 skin:4.80
GeneChip cerebrum:3.64 cerebellum:3.67 brain stem:3.65 corpus callosum/glia:3.76 pineal gland:- peripheral nerve:4.27 spine:3.91 retina:- eye:- artery/aorta:4.53 vein:3.78 lymphnode:3.51 peripheral blood:- spleen:3.28 thymus:3.86 bone marrow:3.63 adipose:4.56 bone:- skin:3.98
CAGE cerebrum:0.92 cerebellum:- brain stem:0.93 corpus callosum/glia:1.13 pineal gland:1.00 peripheral nerve:- spine:1.56 retina:- eye:- artery/aorta:3.24 vein:2.18 lymphnode:0.12 peripheral blood:- spleen:0 thymus:0.57 bone marrow:- adipose:2.28 bone:- skin:-
RNA-seq cerebrum:0.91 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.67 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:32.80 prostate:101.40 ovary:37.30 testis:- heart:- muscle:20.10 esophagus:- stomach:- intestine:- colon:-     liver/hepato:42.20        lung:14.70    bladder:- kidney:104 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:- salivary:-
GeneChip uterus:3.69 placenta:3.53 prostate:5.96 ovary:3.96 testis:3.65 heart:3.84 muscle:4.98 esophagus:3.49 stomach:3.65 intestine:4.17 colon:3.59 liver/hepato:5.50 lung:4.10 bladder:- kidney:4.96 pituitary:3.81 thyroid/parathyroid:4.94 adrenal gland:3.69 pancreas:4.85 breast:3.77 salivary:4.60
CAGE uterus:1.19 placenta:0.92 prostate:2.52 ovary:2.05 testis:1.50 heart:1.63 muscle:2.10 esophagus:1.01 stomach:- intestine:0.14 colon:0.73     liver/hepato:2.75    lung:3.33 bladder:0.58 kidney:2.96 pituitary:1.91 thyroid/parathyroid:3.53 adrenal gland:- pancreas:3.06 breast:2.74 salivary:2.17
RNA-seq uterus:- placenta:- prostate:1.40 ovary:1.76 testis:2.03 heart:0.62 muscle:1.74 esophagus:- stomach:- intestine:- colon:0.77     liver/hepato:2.52        lung:1.73    bladder:- kidney:3.27 pituitary:- thyroid/parathyroid:4.84 adrenal gland:0.52 pancreas:- breast:3.16 salivary:-

Gene Information

IDs

Refseq ID NM_001608
Gene ID 33
Unigene ID Hs.471277
Probe set ID 206069_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000115361
GTEx ID ENSG00000115361

Orthologous Gene

Mouse[2]  NM_007381
Rat [0]  

Chromosomal Region

2q34  [211,052,663  -  211,090,215]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1438359
1559716
1607358
1774065
1945557
2000272
4022672
8739959
9003458
9714723
10832093
12477932
17500595
18029348
18660489
19913121
20037589
20363655
20628086
20877624
22118674
23281178
24121500
24591516

Gene Ontology  (GO ID)

Biological Process

GO:0042413  carnitine catabolic process
GO:0019254  carnitine metabolic process, CoA-linked
GO:0044242  cellular lipid catabolic process
GO:0044255  cellular lipid metabolic process
GO:0006635  fatty acid beta-oxidation
GO:0033539  fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0042758  long-chain fatty acid catabolic process
GO:0045717  negative regulation of fatty acid biosynthetic process
GO:0046322  negative regulation of fatty acid oxidation
GO:0055114  oxidation reduction
GO:0051289  protein homotetramerization
GO:0090181  regulation of cholesterol metabolic process
GO:0001659  temperature homeostasis

Cellular Component

GO:0005737  cytoplasm
GO:0005759  mitochondrial matrix
GO:0031966  mitochondrial membrane
GO:0005739  mitochondrion

Molecular Function

GO:0000062  acyl-CoA binding
GO:0003995  acyl-CoA dehydrogenase activity
GO:0050660  FAD binding
GO:0004466  long-chain-acyl-CoA dehydrogenase activity
GO:0016401  palmitoyl-CoA oxidase activity