interferon, gamma-inducible protein 16

Synonym

interferon, gamma-inducible protein 16, IFI 16, IFNGIP1, IFI16, Gamma-interferon-inducible protein Ifi-16, PYHIN2, MGC9466

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:48.60

cerebellum:-

brain stem:-

corpus callosum/glia:116.60

pineal gland:-

peripheral nerve:61.30

spine:-

retina:237.30

eye:29.40

artery/aorta:329.70

vein:66.60

lymphnode:293.20

peripheral blood:291.50

spleen:132.30

thymus:438

bone marrow:118.10

adipose:121

bone:230.30

skin:187.20

GeneChip

cerebrum:5.68

cerebellum:4.65

brain stem:6.21

corpus callosum/glia:6.86

pineal gland:-

peripheral nerve:7.60

spine:6.99

retina:-

eye:-

artery/aorta:7.87

vein:8.32

lymphnode:8.69

peripheral blood:-

spleen:8.94

thymus:9.09

bone marrow:7.51

adipose:8.24

bone:-

skin:8.11

CAGE

cerebrum:3.55

cerebellum:-

brain stem:4.08

corpus callosum/glia:3.69

pineal gland:3.54

peripheral nerve:-

spine:5.08

retina:-

eye:-

artery/aorta:3.94

vein:4.87

lymphnode:4.95

peripheral blood:-

spleen:5.47

thymus:5.57

bone marrow:-

adipose:5.54

bone:-

skin:-

RNA-seq

cerebrum:3.24

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.95

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:5.25

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:328.10

placenta:47.40

prostate:78.90

ovary:149.10

testis:47.60

heart:127.70

muscle:40.20

esophagus:-

stomach:148.70

intestine:97.20

colon:76.30

liver/hepato:52.80

lung:146.60

bladder:251.20

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:26.70

breast:37.20

salivary:-

GeneChip

uterus:8.44

placenta:7.26

prostate:7.09

ovary:8.95

testis:5.86

heart:7.57

muscle:5.57

esophagus:8.08

stomach:7.30

intestine:7.23

colon:6.40

liver/hepato:6.42

lung:8.62

bladder:-

kidney:5.47

pituitary:4.94

thyroid/parathyroid:6.91

adrenal gland:7.54

pancreas:6.45

breast:7.72

salivary:6

CAGE

uterus:4.75

placenta:4.13

prostate:4.54

ovary:4.84

testis:3.52

heart:4.38

muscle:3.54

esophagus:4.85

stomach:-

intestine:3.93

colon:3.77

liver/hepato:3.56

lung:4.99

bladder:4.74

kidney:3.93

pituitary:3.23

thyroid/parathyroid:4.04

adrenal gland:-

pancreas:2.41

breast:4.62

salivary:2.90

RNA-seq

uterus:-

placenta:-

prostate:4.76

ovary:5.17

testis:4.73

heart:3.39

muscle:2.44

esophagus:-

stomach:-

intestine:-

colon:5.03

liver/hepato:1.91

lung:5.40

bladder:-

kidney:3.65

pituitary:-

thyroid/parathyroid:4.05

adrenal gland:5.60

pancreas:-

breast:4.27

salivary:-

IDs

Refseq ID	NM_005531
Gene ID	3428
Unigene ID	Hs.380250
Probe set ID	208966_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000163565
GTEx ID	ENSG00000163565

Orthologous Gene

Mouse[6]	NM_001033450, NM_172648, NM_008329, NM_001170853
Rat[1]	NM_001012029, NM_172648, NM_008329, NM_001170853

Chromosomal Region

1q23.1 [158,969,758 - 159,024,945]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR011029	DEATH-like
IPR004020	Pyrin

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0002218	activation of innate immune response
GO:0006914	autophagy
GO:0008283	cell proliferation
GO:0042149	cellular response to glucose starvation
GO:0071479	cellular response to ionizing radiation
GO:0051607	defense response to virus
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0030097	hemopoiesis
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0030224	monocyte differentiation
GO:0030099	myeloid cell differentiation
GO:0043392	negative regulation of DNA binding
GO:0045824	negative regulation of innate immune response
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045071	negative regulation of viral genome replication
GO:0001819	positive regulation of cytokine production
GO:0032731	positive regulation of interleukin-1 beta production
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0032481	positive regulation of type I interferon production
GO:0010506	regulation of autophagy
GO:0006355	regulation of transcription, DNA-dependent
GO:0009615	response to virus
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016607	nuclear speck
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0003690	double-stranded DNA binding
GO:0005515	protein binding
GO:0008134	transcription factor binding

interferon, gamma-inducible protein 16

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function