Indian hedgehog homolog (Drosophila)

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Synonym

Indian hedgehog (IHH), Indian hedgehog homolog (Drosophila), Indian hedgehog (Drosophila) homolog, HHG-2, IHH, HHG2, BDA1, Indian hedgehog protein precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.73 cerebellum:5.78 brain stem:5.71 corpus callosum/glia:5.60 pineal gland:- peripheral nerve:5.55 spine:5.59 retina:- eye:- artery/aorta:5.75 vein:5.90 lymphnode:5.60 peripheral blood:- spleen:5.44 thymus:5.43 bone marrow:5.78 adipose:5.68 bone:- skin:5.66
CAGE cerebrum:0.03 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.34 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.13 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:5.98 placenta:6.22 prostate:5.58 ovary:5.72 testis:5.41 heart:5.89 muscle:6.18 esophagus:5.57 stomach:5.80 intestine:5.94 colon:6.26 liver/hepato:5.86 lung:5.61 bladder:- kidney:5.79 pituitary:5.79 thyroid/parathyroid:5.45 adrenal gland:5.52 pancreas:6.18 breast:5.37 salivary:5.69
CAGE uterus:1.39 placenta:0.16 prostate:0.85 ovary:0.32 testis:0.31 heart:0 muscle:0 esophagus:0.57 stomach:- intestine:4.01 colon:4.30     liver/hepato:1.51    lung:1.35 bladder:0.18 kidney:1.72 pituitary:0 thyroid/parathyroid:0.28 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.56 ovary:0.35 testis:0.39 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:2.19     liver/hepato:0.26        lung:0.53    bladder:- kidney:1.15 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0.01 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_002181
Gene ID 3549
Unigene ID -
Probe set ID 215420_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000163501
GTEx ID ENSG00000163501

Orthologous Gene

Mouse[1]  NM_010544
Rat [0]  

Chromosomal Region

2q35  [219,919,146  -  219,925,189]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7590746
7720571
8824192
9186520
9811851
10050855
10462495
11435703
11455389
11476578
12176676
12368206
12384778
12477932
12525541
12632327
12917489
14520411
14651602
14770182
15105288
15146555
15489334
15839736
16322088
16335952
16871364
17360475
17387386
17486609
17962696
18391951
18391952
18629882
18698484
18788453
18829534
19074837
19213939
19277064
19445942
19453261
19464397
19856079
20007344
20189936
20400458
20546612
20683927
20724312
20839884
20846217
20854074
20881264
20881960
21167467
21640343
21642379
21988832
22123293
22234151
22406540
22469853
22486854
22507129
22750747
23403897
23418531
23468532
23575478
23786654
23883825

Gene Ontology  (GO ID)

Biological Process

GO:0045453  bone resorption
GO:0060220  camera-type eye photoreceptor cell fate commitment
GO:0051216  cartilage development
GO:0001708  cell fate specification
GO:0048469  cell maturation
GO:0007267  cell-cell signaling
GO:0048596  embryonic camera-type eye morphogenesis
GO:0048557  embryonic digestive tract morphogenesis
GO:0009880  embryonic pattern specification
GO:0090136  epithelial cell adhesion
GO:0003382  epithelial cell morphogenesis
GO:0060323  head morphogenesis
GO:0001947  heart looping
GO:0001701  in utero embryonic development
GO:0016539  intein-mediated protein splicing
GO:0035264  multicellular organism growth
GO:0046639  negative regulation of alpha-beta T cell differentiation
GO:0048074  negative regulation of eye pigmentation
GO:0033088  negative regulation of immature T cell proliferation in the thymus
GO:0033085  negative regulation of T cell differentiation in the thymus
GO:0048666  neuron development
GO:0001649  osteoblast differentiation
GO:0031016  pancreas development
GO:0001569  patterning of blood vessels
GO:0046638  positive regulation of alpha-beta T cell differentiation
GO:0032967  positive regulation of collagen biosynthetic process
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045880  positive regulation of smoothened signaling pathway
GO:0033089  positive regulation of T cell differentiation in the thymus
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006029  proteoglycan metabolic process
GO:0006508  proteolysis
GO:0040008  regulation of growth
GO:0003406  retinal pigment epithelium development
GO:0048745  smooth muscle tissue development
GO:0007224  smoothened signaling pathway
GO:0030704  vitelline membrane formation

Cellular Component

GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005886  plasma membrane

Molecular Function

GO:0015485  cholesterol binding
GO:0005113  patched binding
GO:0008233  peptidase activity