chemokine (C-X-C motif) receptor 1

Synonym

CMKAR1, C-C, CKR-1, interleukin 8 receptor, alpha, C-C-CKR-1, IL8RA, CXCR-1, IL-8 receptor type 1, IL-8R A, IL8RBA, CD181 antigen, IL8R1, C-C CKR-1, CD128, CDw128a, CXCR1, High affinity interleukin-8 receptor A, CD181

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:36.40

spleen:567.20

thymus:38.70

bone marrow:59

adipose:-

bone:12.80

skin:-

GeneChip

cerebrum:5.56

cerebellum:5.52

brain stem:5.61

corpus callosum/glia:5.51

pineal gland:-

peripheral nerve:5.68

spine:5.66

retina:-

eye:-

artery/aorta:5.86

vein:5.81

lymphnode:5.57

peripheral blood:-

spleen:5.84

thymus:5.72

bone marrow:6.28

adipose:5.66

bone:-

skin:5.80

CAGE

cerebrum:0.64

cerebellum:-

brain stem:1.29

corpus callosum/glia:0.47

pineal gland:0.49

peripheral nerve:-

spine:1.18

retina:-

eye:-

artery/aorta:1.16

vein:0.70

lymphnode:2.31

peripheral blood:-

spleen:3.59

thymus:0.37

bone marrow:-

adipose:2.14

bone:-

skin:-

RNA-seq

cerebrum:0.06

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.42

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.68

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:3.60

prostate:-

ovary:-

testis:-

heart:25.50

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:-

liver/hepato:21.10

lung:19.60

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.51

placenta:5.60

prostate:5.58

ovary:5.41

testis:5.68

heart:5.65

muscle:5.68

esophagus:5.67

stomach:5.58

intestine:5.89

colon:5.53

liver/hepato:5.59

lung:5.71

bladder:-

kidney:5.63

pituitary:5.87

thyroid/parathyroid:5.65

adrenal gland:5.60

pancreas:6.15

breast:5.71

salivary:5.60

CAGE

uterus:0.53

placenta:1.14

prostate:0.94

ovary:1.31

testis:0.72

heart:1.28

muscle:0.90

esophagus:0.77

stomach:-

intestine:0.48

colon:0.29

liver/hepato:1.54

lung:3.34

bladder:0.58

kidney:0.44

pituitary:0.83

thyroid/parathyroid:0.98

adrenal gland:-

pancreas:0.58

breast:0

salivary:0.36

RNA-seq

uterus:-

placenta:-

prostate:0.75

ovary:0.04

testis:0.82

heart:0.25

muscle:0.42

esophagus:-

stomach:-

intestine:-

colon:0.62

liver/hepato:0.59

lung:3.97

bladder:-

kidney:0.04

pituitary:-

thyroid/parathyroid:0.05

adrenal gland:0.28

pancreas:-

breast:0.13

salivary:-

IDs

Refseq ID	NM_000634
Gene ID	3577
Unigene ID	Hs.194778
Probe set ID	207094_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000163464
GTEx ID	ENSG00000163464

Orthologous Gene

Mouse[1]	NM_178241
Rat[1]	NM_178241

Chromosomal Region

2q35 [219,027,568 - 219,031,725]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR001277	C-X-C chemokine receptor, type 4
IPR000355	Chemokine receptor
IPR017452	GPCR, rhodopsin-like superfamily
IPR001355	Interleukin 8A receptor
IPR000174	Interleukin-8 receptor

GO:0007166	cell surface receptor linked signal transduction
GO:0070098	chemokine-mediated signaling pathway
GO:0006935	chemotaxis
GO:0002407	dendritic cell chemotaxis
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0006954	inflammatory response
GO:0031623	receptor internalization

GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005886	plasma membrane

GO:0004950	chemokine receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0019959	interleukin-8 binding
GO:0004918	interleukin-8 receptor activity

chemokine (C-X-C motif) receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function