pancreatic and duodenal homeobox 1

Synonym

IPF1, IDX-1, Pancreas/duodenum homeobox 1, Insulin promoter factor 1, Islet/duodenum homeobox-1, GSF, IUF1, insulin promoter factor 1 (IPF1), Insulin upstream factor 1, IPF-1, MODY4, STF-1, PDX-1, Glucose-sensitive factor, IUF-1, Somatostatin-transactivating factor 1, PDX1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4.68

cerebellum:4.79

brain stem:4.77

corpus callosum/glia:4.50

pineal gland:-

peripheral nerve:4.27

spine:4.33

retina:-

eye:-

artery/aorta:4.65

vein:4.86

lymphnode:4.23

peripheral blood:-

spleen:4.11

thymus:4.25

bone marrow:4.57

adipose:4.58

bone:-

skin:4.35

CAGE

cerebrum:0.00

cerebellum:-

brain stem:0

corpus callosum/glia:0

pineal gland:0.21

peripheral nerve:-

spine:0.09

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.03

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:204.50

breast:-

salivary:-

GeneChip

uterus:4.39

placenta:4.32

prostate:4.34

ovary:4.41

testis:4.36

heart:4.75

muscle:5.12

esophagus:4.46

stomach:4.47

intestine:4.66

colon:4.87

liver/hepato:4.49

lung:4.47

bladder:-

kidney:4.51

pituitary:4.70

thyroid/parathyroid:4.08

adrenal gland:4.50

pancreas:5.04

breast:4.19

salivary:4.30

CAGE

uterus:0

placenta:0

prostate:0

ovary:0

testis:0

heart:0

muscle:0

esophagus:0

stomach:-

intestine:2.89

colon:1.77

liver/hepato:0

lung:0

bladder:0

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:3.10

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0

ovary:0.00

testis:0.16

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.02

liver/hepato:0.09

lung:0

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0.07

adrenal gland:0

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_000209
Gene ID	3651
Unigene ID	Hs.32938
Probe set ID	210938_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000139515
GTEx ID	ENSG00000139515

Orthologous Gene

Mouse[2]	NM_008814
Rat[2]	NM_008814

Chromosomal Region

13q12.2 [28,494,157 - 28,500,368]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related

Gene Ontology (GO ID)

Biological Process

GO:0007417	central nervous system development
GO:0051594	detection of glucose
GO:0031018	endocrine pancreas development
GO:0031017	exocrine pancreas development
GO:0006091	generation of precursor metabolites and energy
GO:0042593	glucose homeostasis
GO:0006006	glucose metabolic process
GO:0048565	gut development
GO:0030073	insulin secretion
GO:0001889	liver development
GO:0016331	morphogenesis of embryonic epithelium
GO:0008285	negative regulation of cell proliferation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0007263	nitric oxide mediated signal transduction
GO:0009887	organ morphogenesis
GO:0031100	organ regeneration
GO:0010260	organ senescence
GO:0003309	pancreatic B cell differentiation
GO:0010942	positive regulation of cell death
GO:0008284	positive regulation of cell proliferation
GO:0043388	positive regulation of DNA binding
GO:0032024	positive regulation of insulin secretion
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0010157	response to chlorate
GO:0034097	response to cytokine stimulus
GO:0042493	response to drug
GO:0070542	response to fatty acid
GO:0051384	response to glucocorticoid stimulus
GO:0043201	response to leucine
GO:0035094	response to nicotine
GO:0033273	response to vitamin
GO:0009611	response to wounding
GO:0007224	smoothened signaling pathway
GO:0048863	stem cell differentiation
GO:0006366	transcription from RNA polymerase II promoter
GO:0060290	transdifferentiation

Cellular Component

GO:0005829	cytosol
GO:0005634	nucleus

Molecular Function

GO:0003682	chromatin binding
GO:0032403	protein complex binding
GO:0046982	protein heterodimerization activity
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

pancreatic and duodenal homeobox 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function