lysyl-tRNA synthetase

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Synonym

lysyl-tRNA synthetase, Lysine--tRNA ligase, LysRS, Lysyl-tRNA synthetase, KIAA0070, KARS2, KARS

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:115

cerebellum:37.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:92

spine:112.30

retina:474.60

eye:176.30

artery/aorta:60

vein:133.30

lymphnode:212.30

peripheral blood:-

spleen:-

thymus:12.90

bone marrow:118.10

adipose:40.30

bone:12.80

skin:81.60

GeneChip

cerebrum:7.26

cerebellum:7.48

brain stem:7.39

corpus callosum/glia:7.08

pineal gland:-

peripheral nerve:7.81

spine:7.31

retina:-

eye:-

artery/aorta:7.82

vein:7.85

lymphnode:8.03

peripheral blood:-

spleen:7.88

thymus:8.36

bone marrow:7.81

adipose:8.13

bone:-

skin:8.16

CAGE

cerebrum:3.21

cerebellum:-

brain stem:3.38

corpus callosum/glia:3.23

pineal gland:3.76

peripheral nerve:-

spine:3.28

retina:-

eye:-

artery/aorta:3.51

vein:3.96

lymphnode:3.77

peripheral blood:-

spleen:4.04

thymus:4.00

bone marrow:-

adipose:3.65

bone:-

skin:-

RNA-seq

cerebrum:2.77

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.12

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.90

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:82

placenta:58.30

prostate:112.60

ovary:372.60

testis:207.70

heart:166

muscle:40.20

esophagus:-

stomach:106.20

intestine:32.40

colon:84.80

liver/hepato:42.20

lung:112.40

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:80

breast:74.30

salivary:-

GeneChip

uterus:8.20

placenta:7.54

prostate:8.19

ovary:8.67

testis:9.30

heart:8.05

muscle:9.03

esophagus:8.43

stomach:7.81

intestine:8.23

colon:7.96

liver/hepato:7.43

lung:7.92

bladder:-

kidney:7.87

pituitary:7.91

thyroid/parathyroid:7.86

adrenal gland:7.48

pancreas:8.72

breast:8.18

salivary:8.20

CAGE

uterus:3.09

placenta:3.78

prostate:3.92

ovary:3.98

testis:4.16

heart:4.03

muscle:4.73

esophagus:3.98

stomach:-

intestine:3.86

colon:3.63

liver/hepato:4.13

lung:3.66

bladder:4.07

kidney:3.84

pituitary:3.26

thyroid/parathyroid:3.92

adrenal gland:-

pancreas:4.42

breast:3.35

salivary:2.43

RNA-seq

uterus:-

placenta:-

prostate:2.74

ovary:2.57

testis:3.70

heart:3.07

muscle:4.12

esophagus:-

stomach:-

intestine:-

colon:2.92

liver/hepato:1.84

lung:2.37

bladder:-

kidney:2.80

pituitary:-

thyroid/parathyroid:2.86

adrenal gland:2.68

pancreas:-

breast:2.70

salivary:-

IDs

Refseq ID	NM_001130089
Gene ID	3735
Unigene ID	Hs.3100
Probe set ID	200079_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000065427
GTEx ID	ENSG00000065427

Orthologous Gene

Mouse[4]	NM_001130868, NM_053092
Rat [0]

Chromosomal Region

16q23.1 [75,661,622 - 75,681,577]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004364	Aminoacyl-tRNA synthetase, class II (D/K/N)
IPR018150	Aminoacyl-tRNA synthetase, class II (D/K/N)-like
IPR006195	Aminoacyl-tRNA synthetase, class II, conserved domain
IPR002312	Aspartyl-tRNA synthetase, class IIb
IPR018149	Lysyl-tRNA synthetase, class II, C-terminal

GO:0015966	diadenosine tetraphosphate biosynthetic process
GO:0010467	gene expression
GO:0006430	lysyl-tRNA aminoacylation
GO:0006418	tRNA aminoacylation for protein translation
GO:0008033	tRNA processing
GO:0019048	virus-host interaction

GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005576	extracellular region
GO:0015630	microtubule cytoskeleton
GO:0005759	mitochondrial matrix
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0005886	plasma membrane

GO:0016597	amino acid binding
GO:0005524	ATP binding
GO:0004824	lysine-tRNA ligase activity
GO:0046872	metal ion binding
GO:0000049	tRNA binding

lysyl-tRNA synthetase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function