lecithin-cholesterol acyltransferase

Synonym

lecithin-cholesterol acyltransferase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase, LCAT

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:24.90

cerebellum:37.80

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:-

spine:112.30

retina:-

eye:52.90

artery/aorta:-

vein:66.60

lymphnode:20.20

peripheral blood:-

spleen:56.70

thymus:12.90

bone marrow:19.70

adipose:-

bone:12.80

skin:38.40

GeneChip

cerebrum:6.23

cerebellum:6.43

brain stem:6.30

corpus callosum/glia:6.35

pineal gland:-

peripheral nerve:6.49

spine:6.42

retina:-

eye:-

artery/aorta:7.10

vein:6.85

lymphnode:6.40

peripheral blood:-

spleen:6.26

thymus:6.32

bone marrow:6.14

adipose:6.74

bone:-

skin:6.46

CAGE

cerebrum:1.94

cerebellum:-

brain stem:1.61

corpus callosum/glia:2.22

pineal gland:1.08

peripheral nerve:-

spine:2.07

retina:-

eye:-

artery/aorta:0.95

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0.06

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:1.35

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.40

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.83

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:45.60

placenta:25.50

prostate:169

ovary:-

testis:8.70

heart:63.90

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:33.90

liver/hepato:31.70

lung:19.60

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:46.50

salivary:-

GeneChip

uterus:6.53

placenta:6.53

prostate:6.56

ovary:6.37

testis:6.53

heart:6.69

muscle:6.59

esophagus:6.29

stomach:6.31

intestine:6.54

colon:6.43

liver/hepato:6.21

lung:6.58

bladder:-

kidney:6.39

pituitary:6.51

thyroid/parathyroid:6.65

adrenal gland:6.63

pancreas:7.17

breast:6.51

salivary:6.42

CAGE

uterus:0.27

placenta:0

prostate:0.85

ovary:0.32

testis:0.75

heart:0.32

muscle:0.09

esophagus:0.18

stomach:-

intestine:0.07

colon:0.53

liver/hepato:5.14

lung:0.40

bladder:0.69

kidney:0.15

pituitary:0.26

thyroid/parathyroid:0.28

adrenal gland:-

pancreas:0

breast:0

salivary:0.36

RNA-seq

uterus:-

placenta:-

prostate:3.11

ovary:2.17

testis:1.94

heart:1.11

muscle:1.37

esophagus:-

stomach:-

intestine:-

colon:2.22

liver/hepato:5.44

lung:3.24

bladder:-

kidney:1.62

pituitary:-

thyroid/parathyroid:2.43

adrenal gland:2.44

pancreas:-

breast:2.18

salivary:-

IDs

Refseq ID	NM_000229
Gene ID	3931
Unigene ID	Hs.387239
Probe set ID	209402_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000213398
GTEx ID	ENSG00000213398

Orthologous Gene

Mouse[1]	NM_008490
Rat [0]

Chromosomal Region

16q22.1 [67,973,653 - 67,978,414]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0034435	cholesterol esterification
GO:0042632	cholesterol homeostasis
GO:0008203	cholesterol metabolic process
GO:0030301	cholesterol transport
GO:0034375	high-density lipoprotein particle remodeling
GO:0042158	lipoprotein biosynthetic process
GO:0042157	lipoprotein metabolic process
GO:0006656	phosphatidylcholine biosynthetic process
GO:0006644	phospholipid metabolic process
GO:0090107	regulation of high-density lipoprotein particle assembly
GO:0043691	reverse cholesterol transport
GO:0034372	very-low-density lipoprotein particle remodeling

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0034364	high-density lipoprotein particle

Molecular Function

GO:0034186	apolipoprotein A-I binding
GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity
GO:0005515	protein binding

lecithin-cholesterol acyltransferase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function