leukotriene A4 hydrolase

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Synonym

leukotriene A4 hydrolase, Leukotriene A(4) hydrolase, LTA-4 hydrolase, LTA4H, Leukotriene A-4 hydrolase, LTA4

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:154.10

cerebellum:340

brain stem:-

corpus callosum/glia:145.80

pineal gland:-

peripheral nerve:61.30

spine:112.30

retina:-

eye:64.60

artery/aorta:269.80

vein:266.60

lymphnode:202.20

peripheral blood:747

spleen:529.40

thymus:438

bone marrow:452.60

adipose:121

bone:537.40

skin:144

GeneChip

cerebrum:7.38

cerebellum:8.10

brain stem:7.54

corpus callosum/glia:7.32

pineal gland:-

peripheral nerve:7.75

spine:7.50

retina:-

eye:-

artery/aorta:8.20

vein:8.30

lymphnode:8.91

peripheral blood:-

spleen:8.60

thymus:8.42

bone marrow:10.43

adipose:8.21

bone:-

skin:8.61

CAGE

cerebrum:3.84

cerebellum:-

brain stem:3.77

corpus callosum/glia:3.78

pineal gland:4.54

peripheral nerve:-

spine:3.82

retina:-

eye:-

artery/aorta:4.26

vein:4.17

lymphnode:4.76

peripheral blood:-

spleen:4.91

thymus:4.33

bone marrow:-

adipose:4.51

bone:-

skin:-

RNA-seq

cerebrum:3.53

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.09

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.51

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:227.80

placenta:61.90

prostate:123.90

ovary:149.10

testis:160.10

heart:217.10

muscle:20.10

esophagus:-

stomach:169.90

intestine:421.20

colon:110.20

liver/hepato:95

lung:283.50

bladder:125.60

kidney:405.50

pituitary:347.90

thyroid/parathyroid:-

adrenal gland:457.10

pancreas:62.20

breast:83.60

salivary:-

GeneChip

uterus:8.66

placenta:6.79

prostate:8.58

ovary:9.42

testis:7.98

heart:7.92

muscle:8.19

esophagus:9.44

stomach:8.42

intestine:8.61

colon:8.43

liver/hepato:7.72

lung:10.40

bladder:-

kidney:8.31

pituitary:8.39

thyroid/parathyroid:8.59

adrenal gland:8.74

pancreas:8.60

breast:8.53

salivary:7.91

CAGE

uterus:4.58

placenta:3.56

prostate:4.62

ovary:5.05

testis:3.92

heart:3.98

muscle:3.81

esophagus:5.04

stomach:-

intestine:4.84

colon:4.52

liver/hepato:3.98

lung:5.54

bladder:4.58

kidney:4.43

pituitary:4.61

thyroid/parathyroid:4.73

adrenal gland:-

pancreas:4.10

breast:4.08

salivary:4.16

RNA-seq

uterus:-

placenta:-

prostate:5.52

ovary:5.96

testis:4.68

heart:3.81

muscle:4.38

esophagus:-

stomach:-

intestine:-

colon:5.19

liver/hepato:3.33

lung:5.93

bladder:-

kidney:4.53

pituitary:-

thyroid/parathyroid:4.67

adrenal gland:4.66

pancreas:-

breast:4.92

salivary:-

IDs

Refseq ID	NM_000895
Gene ID	4048
Unigene ID	Hs.524648
Probe set ID	208771_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000111144
GTEx ID	ENSG00000111144

Orthologous Gene

Mouse[1]	NM_008517
Rat[2]	NM_001030031

Chromosomal Region

12q23.1 [96,394,606 - 96,437,298]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR012777	Leukotriene A-4 hydrolase/aminopeptidase
IPR001930	Peptidase M1, membrane alanine aminopeptidase

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0019369	arachidonic acid metabolic process
GO:0006954	inflammatory response
GO:0019370	leukotriene biosynthetic process
GO:0006691	leukotriene metabolic process
GO:0043171	peptide catabolic process
GO:0006508	proteolysis

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005730	nucleolus
GO:0005634	nucleus

Molecular Function

GO:0004177	aminopeptidase activity
GO:0004301	epoxide hydrolase activity
GO:0004463	leukotriene-A4 hydrolase activity
GO:0008237	metallopeptidase activity
GO:0008233	peptidase activity
GO:0008270	zinc ion binding

leukotriene A4 hydrolase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function